HuLG000171

Entrez Gene ID

240

Official Gene Symbol

ALOX5

Synonyms

5NLO|5NLOX|5LPG|LOG5|MGC163204

Gene name

arachidonate 5-lipoxygenase

Gene Type

protein-coding

Chromosome

10

Genomics Location

10q11.2

Known cancer genes

Yes

Protein products

Arachidonate 5-lipoxygenase

Related liver disease name

Liver fibrosis and liver cirrhosis

Database cross reference

HGNC:435
MIM:152390
Ensembl:ENSG00000012779
HPRD:01065
RefSeq Genomic nucleotide accession:AC_000053
RefSeq Genomic nucleotide gi:89161186

GO annotation

GO:0002526

acute inflammatory response

GO:0002540

leukotriene production involved in inflammatory response

GO:0004051

arachidonate 5-lipoxygenase activity

GO:0005506

iron ion binding

GO:0005515

protein binding

GO:0005625

soluble fraction

GO:0005634

nucleus

GO:0005635

nuclear envelope

GO:0005641

nuclear envelope lumen

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0006691

leukotriene metabolic process

GO:0006692

prostanoid metabolic process

GO:0007584

response to nutrient

GO:0016020

membrane

GO:0016165

lipoxygenase activity

GO:0016363

nuclear matrix

GO:0016491

oxidoreductase activity

GO:0019233

sensory perception of pain

GO:0019369

arachidonic acid metabolic process

GO:0019370

leukotriene biosynthetic process

GO:0019372

lipoxygenase pathway

GO:0030425

dendrite

GO:0031965

nuclear membrane

GO:0042383

sarcolemma

GO:0042446

hormone biosynthetic process

GO:0045907

positive regulation of vasoconstriction

GO:0046872

metal ion binding