Gene basic information
| LiverAtlas Gene ID |
HuLG000172 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
ALOX5AP |
|
Synonyms |
FLAP |
|
Gene name |
arachidonate 5-lipoxygenase-activating protein |
|
Gene Type |
protein-coding |
|
Chromosome |
13 |
|
Genomics Location |
13q12 |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:436
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0002540 |
leukotriene production involved in inflammatory response |
|
GO:0004051 |
arachidonate 5-lipoxygenase activity |
|
GO:0004464 |
leukotriene-C4 synthase activity |
|
GO:0004602 |
glutathione peroxidase activity |
|
GO:0005515 |
protein binding |
|
GO:0005634 |
nucleus |
|
GO:0005635 |
nuclear envelope |
|
GO:0005783 |
endoplasmic reticulum |
|
GO:0005789 |
endoplasmic reticulum membrane |
|
GO:0005792 |
microsome |
|
GO:0008047 |
enzyme activator activity |
|
GO:0016020 |
membrane |
|
GO:0016021 |
integral to membrane |
|
GO:0019370 |
leukotriene biosynthetic process |
|
GO:0019899 |
enzyme binding |
|
GO:0031965 |
nuclear membrane |
|
GO:0042803 |
protein homodimerization activity |
|
GO:0046982 |
protein heterodimerization activity |
|
GO:0047485 |
protein N-terminus binding |
|
GO:0050544 |
arachidonic acid binding |
|
GO:0070207 |
protein homotrimerization |
|
GO:0071277 |
cellular response to calcium ion |
