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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000178

Entrez Gene ID

249

Official Gene Symbol

ALPL

Synonyms

APNTNAP|APTNAP|FLJ40094|FLJ93059|HOPS|MGC161443|MGC167935|TNAP|TNSALP

Gene name

alkaline phosphatase, liver/bone/kidney

Gene Type

protein-coding

Chromosome

1

Genomics Location

1p36.12

Known cancer genes

Yes

Protein products

Alkaline phosphatase

Alkaline phosphatase

Alkaline phosphatase, tissue-nonspecific isozyme

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:438
MIM:171760
Ensembl:ENSG00000162551
HPRD:01377
RefSeq Genomic nucleotide accession:AC_000044
RefSeq Genomic nucleotide gi:89161184

Liver relevance

Liver sepcificity

Yes/No

Yes

Evidence

BodyMap

Quality score

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0001501

skeletal system development

GO:0004035

alkaline phosphatase activity

GO:0005615

extracellular space

GO:0005737

cytoplasm

GO:0005886

plasma membrane

GO:0016021

integral to membrane

GO:0016787

hydrolase activity

GO:0031214

biomineral tissue development

GO:0031225

anchored to membrane

GO:0032496

response to lipopolysaccharide

GO:0033280

response to vitamin D

GO:0046677

response to antibiotic

GO:0046872

metal ion binding

GO:0051384

response to glucocorticoid stimulus

GO:0071407

cellular response to organic cyclic compound

GO:0071529

cementum mineralization