Gene basic information
| LiverAtlas Gene ID |
HuLG000225 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
APAF1 |
|
Synonyms |
APAFN1|CED4|DKFZp781B1145 |
|
Gene name |
apoptotic peptidase activating factor 1 |
|
Gene Type |
protein-coding |
|
Chromosome |
12 |
|
Genomics Location |
12q23 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:576
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000166 |
nucleotide binding |
|
GO:0005515 |
protein binding |
|
GO:0005524 |
ATP binding |
|
GO:0005622 |
intracellular |
|
GO:0005634 |
nucleus |
|
GO:0005730 |
nucleolus |
|
GO:0005737 |
cytoplasm |
|
GO:0005794 |
Golgi apparatus |
|
GO:0005829 |
cytosol |
|
GO:0006915 |
apoptosis |
|
GO:0006919 |
activation of caspase activity |
|
GO:0006952 |
defense response |
|
GO:0007399 |
nervous system development |
|
GO:0008629 |
induction of apoptosis by intracellular signals |
|
GO:0008635 |
activation of caspase activity by cytochrome c |
|
GO:0008656 |
caspase activator activity |
|
GO:0042981 |
regulation of apoptosis |
