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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000234

Entrez Gene ID

326

Official Gene Symbol

AIRE

Synonyms

AIRE1|APECED|APS1|APSI|PGA1

Gene name

autoimmune regulator

Gene Type

protein-coding

Chromosome

21

Genomics Location

21q22.3

Protein products

Autoimmune regulator

AIRE protein

APS protein

APS protein

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Chronic hepatitis

Autoimmune hepatitis

Primary biliary cirrhosis

Autoimmune hepatitis

Primary sclerosing cholangitis

Database cross reference

HGNC:360
MIM:607358
Ensembl:ENSG00000160224
HPRD:06301
RefSeq Genomic nucleotide accession:AC_000064
RefSeq Genomic nucleotide gi:89161201

 

Ontology annotation

GO ID

GO annotation

GO:0003677

DNA binding

GO:0003682

chromatin binding

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005737

cytoplasm

GO:0006355

regulation of transcription, DNA-dependent

GO:0006955

immune response

GO:0006959

humoral immune response

GO:0008270

zinc ion binding

GO:0042393

histone binding

GO:0045182

translation regulator activity

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

GO:0046872

metal ion binding