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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000240

Entrez Gene ID

332

Official Gene Symbol

BIRC5

Synonyms

API4|EPRN1

Gene name

baculoviral IAP repeat containing 5

Gene Type

protein-coding

Chromosome

17

Genomics Location

17q25

Known cancer genes

Yes

Protein products

Survivin isoform Ex2+4/2B/3B

Baculoviral IAP repeat-containing protein 5

Baculoviral IAP repeat-containing 5

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:593
MIM:603352
Ensembl:ENSG00000089685
HPRD:04520
RefSeq Genomic nucleotide accession:AC_000060
RefSeq Genomic nucleotide gi:89161195

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000086

G2/M transition of mitotic cell cycle

GO:0000087

M phase of mitotic cell cycle

GO:0000228

nuclear chromosome

GO:0000236

mitotic prometaphase

GO:0000278

mitotic cell cycle

GO:0000775

chromosome, centromeric region

GO:0000910

cytokinesis

GO:0004869

cysteine-type endopeptidase inhibitor activity

GO:0005515

protein binding

GO:0005622

intracellular

GO:0005634

nucleus

GO:0005730

nucleolus

GO:0005737

cytoplasm

GO:0005814

centriole

GO:0005819

spindle

GO:0005829

cytosol

GO:0005856

cytoskeleton

GO:0005876

spindle microtubule

GO:0005881

cytoplasmic microtubule

GO:0006915

apoptosis

GO:0006916

anti-apoptosis

GO:0007059

chromosome segregation

GO:0007067

mitosis

GO:0008017

microtubule binding

GO:0008270

zinc ion binding

GO:0008536

Ran GTPase binding

GO:0015631

tubulin binding

GO:0019899

enzyme binding

GO:0030414

peptidase inhibitor activity

GO:0030496

midbody

GO:0031021

interphase microtubule organizing center

GO:0031503

protein complex localization

GO:0031536

positive regulation of exit from mitosis

GO:0031577

spindle checkpoint

GO:0032133

chromosome passenger complex

GO:0042802

identical protein binding

GO:0042803

protein homodimerization activity

GO:0043027

caspase inhibitor activity

GO:0043154

negative regulation of caspase activity

GO:0045931

positive regulation of mitotic cell cycle

GO:0046872

metal ion binding

GO:0046982

protein heterodimerization activity

GO:0048037

cofactor binding

GO:0050897

cobalt ion binding

GO:0051087

chaperone binding

GO:0051301

cell division

GO:0051303

establishment of chromosome localization