Gene basic information
| LiverAtlas Gene ID |
HuLG000243 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
APOA1 |
|
Synonyms |
MGC117399 |
|
Gene name |
apolipoprotein A-I |
|
Gene Type |
protein-coding |
|
Chromosome |
11 |
|
Genomics Location |
11q23-q24 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:600
|
Liver relevance
| Liver sepcificity |
Yes/No |
Yes |
|
Evidence |
Translational level from literatures |
|
|
Quality score |
|
|
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net OncoDB |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0001540 |
beta-amyloid binding |
|
GO:0001932 |
regulation of protein phosphorylation |
|
GO:0001935 |
endothelial cell proliferation |
|
GO:0002576 |
platelet degranulation |
|
GO:0002740 |
negative regulation of cytokine secretion involved in immune response |
|
GO:0005319 |
lipid transporter activity |
|
GO:0005515 |
protein binding |
|
GO:0005543 |
phospholipid binding |
|
GO:0005576 |
extracellular region |
|
GO:0005615 |
extracellular space |
|
GO:0005788 |
endoplasmic reticulum lumen |
|
GO:0005886 |
plasma membrane |
|
GO:0006629 |
lipid metabolic process |
|
GO:0006644 |
phospholipid metabolic process |
|
GO:0006656 |
phosphatidylcholine biosynthetic process |
|
GO:0006695 |
cholesterol biosynthetic process |
|
GO:0007186 |
G-protein coupled receptor protein signaling pathway |
|
GO:0007596 |
blood coagulation |
|
GO:0008035 |
high-density lipoprotein particle binding |
|
GO:0008202 |
steroid metabolic process |
|
GO:0008203 |
cholesterol metabolic process |
|
GO:0008211 |
glucocorticoid metabolic process |
|
GO:0010873 |
positive regulation of cholesterol esterification |
|
GO:0010903 |
negative regulation of very-low-density lipoprotein particle remodeling |
|
GO:0015485 |
cholesterol binding |
|
GO:0017127 |
cholesterol transporter activity |
|
GO:0019899 |
enzyme binding |
|
GO:0019915 |
lipid storage |
|
GO:0030139 |
endocytic vesicle |
|
GO:0030141 |
stored secretory granule |
|
GO:0030168 |
platelet activation |
|
GO:0030300 |
regulation of intestinal cholesterol absorption |
|
GO:0030301 |
cholesterol transport |
|
GO:0030325 |
adrenal gland development |
|
GO:0031410 |
cytoplasmic vesicle |
|
GO:0032488 |
Cdc42 protein signal transduction |
|
GO:0033344 |
cholesterol efflux |
|
GO:0033700 |
phospholipid efflux |
|
GO:0034190 |
apolipoprotein receptor binding |
|
GO:0034191 |
apolipoprotein A-I receptor binding |
|
GO:0034361 |
very-low-density lipoprotein particle |
|
GO:0034364 |
high-density lipoprotein particle |
|
GO:0034366 |
spherical high-density lipoprotein particle |
|
GO:0034375 |
high-density lipoprotein particle remodeling |
|
GO:0034380 |
high-density lipoprotein particle assembly |
|
GO:0034384 |
high-density lipoprotein particle clearance |
|
GO:0042157 |
lipoprotein metabolic process |
|
GO:0042158 |
lipoprotein biosynthetic process |
|
GO:0042632 |
cholesterol homeostasis |
|
GO:0042802 |
identical protein binding |
|
GO:0043534 |
blood vessel endothelial cell migration |
|
GO:0043691 |
reverse cholesterol transport |
|
GO:0044255 |
cellular lipid metabolic process |
|
GO:0050713 |
negative regulation of interleukin-1 beta secretion |
|
GO:0050821 |
protein stabilization |
|
GO:0051345 |
positive regulation of hydrolase activity |
|
GO:0051346 |
negative regulation of hydrolase activity |
|
GO:0051347 |
positive regulation of transferase activity |
|
GO:0055085 |
transmembrane transport |
|
GO:0060228 |
phosphatidylcholine-sterol O-acyltransferase activator activity |
|
GO:0070508 |
cholesterol import |
|
GO:0070653 |
high-density lipoprotein particle receptor binding |
