Gene basic information
| LiverAtlas Gene ID |
HuLG000244 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
APOA2 |
|
Synonyms |
ApoNAII|ApoANII|apoAII |
|
Gene name |
apolipoprotein A-II |
|
Gene Type |
protein-coding |
|
Chromosome |
1 |
|
Genomics Location |
1q21-q23 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:601
|
Liver relevance
| Liver sepcificity |
Yes/No |
Yes |
|
Evidence |
Translational level from literatures |
|
|
Quality score |
|
|
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0002526 |
acute inflammatory response |
|
GO:0002740 |
negative regulation of cytokine secretion involved in immune response |
|
GO:0005319 |
lipid transporter activity |
|
GO:0005515 |
protein binding |
|
GO:0005543 |
phospholipid binding |
|
GO:0005576 |
extracellular region |
|
GO:0005615 |
extracellular space |
|
GO:0005788 |
endoplasmic reticulum lumen |
|
GO:0006457 |
protein folding |
|
GO:0006629 |
lipid metabolic process |
|
GO:0006641 |
triglyceride metabolic process |
|
GO:0006656 |
phosphatidylcholine biosynthetic process |
|
GO:0006810 |
transport |
|
GO:0008035 |
high-density lipoprotein particle binding |
|
GO:0008203 |
cholesterol metabolic process |
|
GO:0008289 |
lipid binding |
|
GO:0009395 |
phospholipid catabolic process |
|
GO:0009749 |
response to glucose stimulus |
|
GO:0010873 |
positive regulation of cholesterol esterification |
|
GO:0010903 |
negative regulation of very-low-density lipoprotein particle remodeling |
|
GO:0015485 |
cholesterol binding |
|
GO:0017127 |
cholesterol transporter activity |
|
GO:0030300 |
regulation of intestinal cholesterol absorption |
|
GO:0031100 |
organ regeneration |
|
GO:0031210 |
phosphatidylcholine binding |
|
GO:0031647 |
regulation of protein stability |
|
GO:0032375 |
negative regulation of cholesterol transport |
|
GO:0033344 |
cholesterol efflux |
|
GO:0033700 |
phospholipid efflux |
|
GO:0034190 |
apolipoprotein receptor binding |
|
GO:0034361 |
very-low-density lipoprotein particle |
|
GO:0034364 |
high-density lipoprotein particle |
|
GO:0034366 |
spherical high-density lipoprotein particle |
|
GO:0034370 |
triglyceride-rich lipoprotein particle remodeling |
|
GO:0034374 |
low-density lipoprotein particle remodeling |
|
GO:0034375 |
high-density lipoprotein particle remodeling |
|
GO:0034380 |
high-density lipoprotein particle assembly |
|
GO:0034384 |
high-density lipoprotein particle clearance |
|
GO:0042157 |
lipoprotein metabolic process |
|
GO:0042493 |
response to drug |
|
GO:0042627 |
chylomicron |
|
GO:0042632 |
cholesterol homeostasis |
|
GO:0042803 |
protein homodimerization activity |
|
GO:0043627 |
response to estrogen stimulus |
|
GO:0043691 |
reverse cholesterol transport |
|
GO:0044255 |
cellular lipid metabolic process |
|
GO:0044419 |
interspecies interaction between organisms |
|
GO:0045416 |
positive regulation of interleukin-8 biosynthetic process |
|
GO:0046340 |
diacylglycerol catabolic process |
|
GO:0046982 |
protein heterodimerization activity |
|
GO:0050995 |
negative regulation of lipid catabolic process |
|
GO:0050996 |
positive regulation of lipid catabolic process |
|
GO:0051384 |
response to glucocorticoid stimulus |
|
GO:0055102 |
lipase inhibitor activity |
|
GO:0060192 |
negative regulation of lipase activity |
|
GO:0060228 |
phosphatidylcholine-sterol O-acyltransferase activator activity |
|
GO:0060621 |
negative regulation of cholesterol import |
|
GO:0060695 |
negative regulation of cholesterol transporter activity |
|
GO:0070653 |
high-density lipoprotein particle receptor binding |
