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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000245

Entrez Gene ID

337

Official Gene Symbol

APOA4

Synonyms

MGC142154|MGC142156

Gene name

apolipoprotein A-IV

Gene Type

protein-coding

Chromosome

11

Genomics Location

11q23

Protein products

Apolipoprotein A-IV

APOA4 protein

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:602
MIM:107690
Ensembl:ENSG00000110244
HPRD:00130



Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0002227

innate immune response in mucosa

GO:0005319

lipid transporter activity

GO:0005507

copper ion binding

GO:0005576

extracellular region

GO:0005615

extracellular space

GO:0005788

endoplasmic reticulum lumen

GO:0006629

lipid metabolic process

GO:0006810

transport

GO:0006869

lipid transport

GO:0006982

response to lipid hydroperoxide

GO:0007159

leukocyte cell-cell adhesion

GO:0008203

cholesterol metabolic process

GO:0008289

lipid binding

GO:0009986

cell surface

GO:0010873

positive regulation of cholesterol esterification

GO:0010898

positive regulation of triglyceride catabolic process

GO:0016209

antioxidant activity

GO:0017127

cholesterol transporter activity

GO:0019430

removal of superoxide radicals

GO:0030300

regulation of intestinal cholesterol absorption

GO:0031210

phosphatidylcholine binding

GO:0032374

regulation of cholesterol transport

GO:0033344

cholesterol efflux

GO:0033700

phospholipid efflux

GO:0034361

very-low-density lipoprotein particle

GO:0034364

high-density lipoprotein particle

GO:0034371

chylomicron remodeling

GO:0034372

very-low-density lipoprotein particle remodeling

GO:0034375

high-density lipoprotein particle remodeling

GO:0034378

chylomicron assembly

GO:0034445

negative regulation of plasma lipoprotein particle oxidation

GO:0035634

response to stilbenoid

GO:0042157

lipoprotein metabolic process

GO:0042627

chylomicron

GO:0042632

cholesterol homeostasis

GO:0042744

hydrogen peroxide catabolic process

GO:0042803

protein homodimerization activity

GO:0043499

eukaryotic cell surface binding

GO:0043691

reverse cholesterol transport

GO:0044240

multicellular organismal lipid catabolic process

GO:0045723

positive regulation of fatty acid biosynthetic process

GO:0046470

phosphatidylcholine metabolic process

GO:0051006

positive regulation of lipoprotein lipase activity

GO:0055088

lipid homeostasis

GO:0060228

phosphatidylcholine-sterol O-acyltransferase activator activity

GO:0065005

protein-lipid complex assembly