Gene basic information
| LiverAtlas Gene ID |
HuLG000246 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
APOB |
|
Synonyms |
FLDB|LDLCQ4 |
|
Gene name |
apolipoprotein B (including Ag(x) antigen) |
|
Gene Type |
protein-coding |
|
Chromosome |
2 |
|
Genomics Location |
2p24-p23 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:603
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0001701 |
in utero embryonic development |
|
GO:0005319 |
lipid transporter activity |
|
GO:0005543 |
phospholipid binding |
|
GO:0005576 |
extracellular region |
|
GO:0005615 |
extracellular space |
|
GO:0005783 |
endoplasmic reticulum |
|
GO:0005788 |
endoplasmic reticulum lumen |
|
GO:0005789 |
endoplasmic reticulum membrane |
|
GO:0005792 |
microsome |
|
GO:0005886 |
plasma membrane |
|
GO:0006629 |
lipid metabolic process |
|
GO:0006642 |
triglyceride mobilization |
|
GO:0006810 |
transport |
|
GO:0006898 |
receptor-mediated endocytosis |
|
GO:0007283 |
spermatogenesis |
|
GO:0007399 |
nervous system development |
|
GO:0007596 |
blood coagulation |
|
GO:0008201 |
heparin binding |
|
GO:0008202 |
steroid metabolic process |
|
GO:0008203 |
cholesterol metabolic process |
|
GO:0009566 |
fertilization |
|
GO:0009615 |
response to virus |
|
GO:0009743 |
response to carbohydrate stimulus |
|
GO:0009791 |
post-embryonic development |
|
GO:0010008 |
endosome membrane |
|
GO:0010269 |
response to selenium ion |
|
GO:0010744 |
positive regulation of macrophage derived foam cell differentiation |
|
GO:0010884 |
positive regulation of lipid storage |
|
GO:0010886 |
positive regulation of cholesterol storage |
|
GO:0012506 |
vesicle membrane |
|
GO:0016042 |
lipid catabolic process |
|
GO:0017127 |
cholesterol transporter activity |
|
GO:0019433 |
triglyceride catabolic process |
|
GO:0019899 |
enzyme binding |
|
GO:0030168 |
platelet activation |
|
GO:0030301 |
cholesterol transport |
|
GO:0030317 |
sperm motility |
|
GO:0030669 |
clathrin-coated endocytic vesicle membrane |
|
GO:0031904 |
endosome lumen |
|
GO:0031983 |
vesicle lumen |
|
GO:0032496 |
response to lipopolysaccharide |
|
GO:0034359 |
mature chylomicron |
|
GO:0034360 |
chylomicron remnant |
|
GO:0034361 |
very-low-density lipoprotein particle |
|
GO:0034362 |
low-density lipoprotein particle |
|
GO:0034363 |
intermediate-density lipoprotein particle |
|
GO:0034374 |
low-density lipoprotein particle remodeling |
|
GO:0034379 |
very-low-density lipoprotein particle assembly |
|
GO:0034383 |
low-density lipoprotein particle clearance |
|
GO:0042157 |
lipoprotein metabolic process |
|
GO:0042158 |
lipoprotein biosynthetic process |
|
GO:0042159 |
lipoprotein catabolic process |
|
GO:0042627 |
chylomicron |
|
GO:0042632 |
cholesterol homeostasis |
|
GO:0042953 |
lipoprotein transport |
|
GO:0045540 |
regulation of cholesterol biosynthetic process |
|
GO:0046982 |
protein heterodimerization activity |
|
GO:0048844 |
artery morphogenesis |
|
GO:0050750 |
low-density lipoprotein particle receptor binding |
|
GO:0050900 |
leukocyte migration |
|
GO:0071356 |
cellular response to tumor necrosis factor |
|
GO:0071379 |
cellular response to prostaglandin stimulus |
