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Gene basic information

LiverAtlas Gene ID	HuLG000248
Entrez Gene ID	341
Official Gene Symbol	APOC1
Gene name	apolipoprotein C-I
Gene Type	protein-coding
Chromosome	19
Genomics Location	19q13.2
Known cancer genes	Yes
Protein products	Apolipoprotein C-I Apolipoprotein C-I
Related liver disease name	Hepatitis Viral hepatitis Hepatitis A Hepatitis B Hepatitis C Hepatitis D Hepatitis E Hepatocellular carcinoma
Database cross reference	HGNC:607 MIM:107710 Ensembl:ENSG00000130208 HPRD:00131 RefSeq Genomic nucleotide accession:AC_000062 RefSeq Genomic nucleotide gi:89161197

Liver relevance

HCC significant genes	Yes/No	Yes
	Evidence	EHCO HCC.net OncoDB
	Quality score

Ontology annotation

GO ID	GO annotation
GO:0004859	phospholipase inhibitor activity
GO:0005504	fatty acid binding
GO:0005576	extracellular region
GO:0005783	endoplasmic reticulum
GO:0006629	lipid metabolic process
GO:0006641	triglyceride metabolic process
GO:0006810	transport
GO:0008203	cholesterol metabolic process
GO:0010873	positive regulation of cholesterol esterification
GO:0010900	negative regulation of phosphatidylcholine catabolic process
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance
GO:0031210	phosphatidylcholine binding
GO:0032368	regulation of lipid transport
GO:0032374	regulation of cholesterol transport
GO:0032375	negative regulation of cholesterol transport
GO:0033344	cholesterol efflux
GO:0033700	phospholipid efflux
GO:0034361	very-low-density lipoprotein particle
GO:0034364	high-density lipoprotein particle
GO:0034369	plasma lipoprotein particle remodeling
GO:0034375	high-density lipoprotein particle remodeling
GO:0034379	very-low-density lipoprotein particle assembly
GO:0034382	chylomicron remnant clearance
GO:0034447	very-low-density lipoprotein particle clearance
GO:0042157	lipoprotein metabolic process
GO:0042627	chylomicron
GO:0045717	negative regulation of fatty acid biosynthetic process
GO:0045833	negative regulation of lipid metabolic process
GO:0048261	negative regulation of receptor-mediated endocytosis
GO:0050995	negative regulation of lipid catabolic process
GO:0051005	negative regulation of lipoprotein lipase activity
GO:0055102	lipase inhibitor activity
GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity