HuLG000250

Entrez Gene ID

344

Official Gene Symbol

APOC2

Synonyms

APONCII|APOCNII|MGC75082

Gene name

apolipoprotein C-II

Gene Type

protein-coding

Chromosome

19

Genomics Location

19q13.2

Known cancer genes

Yes

Protein products

Apolipoprotein C-II

APOC2 protein

Related liver disease name

Hepatitis

Viral hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Hepatocellular carcinoma

Database cross reference

HGNC:609
MIM:608083
Ensembl:ENSG00000234906
HPRD:07457
RefSeq Genomic nucleotide accession:AC_000062
RefSeq Genomic nucleotide gi:89161197

Yes/No

Yes

Evidence

BodyMap

Quality score

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

GO annotation

GO:0005576

extracellular region

GO:0005615

extracellular space

GO:0006629

lipid metabolic process

GO:0006810

transport

GO:0006869

lipid transport

GO:0008047

enzyme activator activity

GO:0008289

lipid binding

GO:0010518

positive regulation of phospholipase activity

GO:0010898

positive regulation of triglyceride catabolic process

GO:0010902

positive regulation of very-low-density lipoprotein particle remodeling

GO:0010916

negative regulation of very-low-density lipoprotein particle clearance

GO:0016004

phospholipase activator activity

GO:0016042

lipid catabolic process

GO:0032375

negative regulation of cholesterol transport

GO:0033344

cholesterol efflux

GO:0033700

phospholipid efflux

GO:0034361

very-low-density lipoprotein particle

GO:0034362

low-density lipoprotein particle

GO:0034363

intermediate-density lipoprotein particle

GO:0034366

spherical high-density lipoprotein particle

GO:0034370

triglyceride-rich lipoprotein particle remodeling

GO:0034371

chylomicron remodeling

GO:0034372

very-low-density lipoprotein particle remodeling

GO:0034382

chylomicron remnant clearance

GO:0034384

high-density lipoprotein particle clearance

GO:0042157

lipoprotein metabolic process

GO:0042493

response to drug

GO:0042627

chylomicron

GO:0042632

cholesterol homeostasis

GO:0042803

protein homodimerization activity

GO:0042953

lipoprotein transport

GO:0043274

phospholipase binding

GO:0043691

reverse cholesterol transport

GO:0045723

positive regulation of fatty acid biosynthetic process

GO:0045833

negative regulation of lipid metabolic process

GO:0048261

negative regulation of receptor-mediated endocytosis

GO:0051006

positive regulation of lipoprotein lipase activity

GO:0055102

lipase inhibitor activity

GO:0060230

lipoprotein lipase activator activity

GO:0060697

positive regulation of phospholipid catabolic process

GO:0070328

triglyceride homeostasis