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Gene basic information

LiverAtlas Gene ID	HuLG000251
Entrez Gene ID	345
Official Gene Symbol	APOC3
Synonyms	APOCIII\|MGC150353
Gene name	apolipoprotein C-III
Gene Type	protein-coding
Chromosome	11
Genomics Location	11q23.1-q23.2
Protein products	Apolipoprotein C-III Apolipoprotein C-III Apolipoprotein C-III variant 1
Related liver disease name	Hepatitis Viral hepatitis Hepatitis A Hepatitis B Hepatitis C Hepatitis D Hepatitis E Drug-induced hepatitis Hepatocellular carcinoma
Database cross reference	HGNC:610 MIM:107720 Ensembl:ENSG00000110245 HPRD:00132 RefSeq Genomic nucleotide accession:AC_000054 RefSeq Genomic nucleotide gi:89161188

Liver relevance

Liver sepcificity	Yes/No	Yes
	Evidence	BodyMap
	Quality score
HCC significant genes	Yes/No	Yes
	Evidence	EHCO
	Quality score

Ontology annotation

GO ID	GO annotation
GO:0005543	phospholipid binding
GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0006629	lipid metabolic process
GO:0006641	triglyceride metabolic process
GO:0006642	triglyceride mobilization
GO:0006810	transport
GO:0006869	lipid transport
GO:0007186	G-protein coupled receptor protein signaling pathway
GO:0008203	cholesterol metabolic process
GO:0010897	negative regulation of triglyceride catabolic process
GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance
GO:0010987	negative regulation of high-density lipoprotein particle clearance
GO:0010989	negative regulation of low-density lipoprotein particle clearance
GO:0015485	cholesterol binding
GO:0019433	triglyceride catabolic process
GO:0030234	enzyme regulator activity
GO:0032488	Cdc42 protein signal transduction
GO:0033344	cholesterol efflux
GO:0033700	phospholipid efflux
GO:0034361	very-low-density lipoprotein particle
GO:0034363	intermediate-density lipoprotein particle
GO:0034366	spherical high-density lipoprotein particle
GO:0034375	high-density lipoprotein particle remodeling
GO:0034379	very-low-density lipoprotein particle assembly
GO:0034382	chylomicron remnant clearance
GO:0042157	lipoprotein metabolic process
GO:0042627	chylomicron
GO:0042632	cholesterol homeostasis
GO:0043691	reverse cholesterol transport
GO:0045717	negative regulation of fatty acid biosynthetic process
GO:0045833	negative regulation of lipid metabolic process
GO:0048261	negative regulation of receptor-mediated endocytosis
GO:0050995	negative regulation of lipid catabolic process
GO:0051005	negative regulation of lipoprotein lipase activity
GO:0055102	lipase inhibitor activity
GO:0060621	negative regulation of cholesterol import
GO:0070328	triglyceride homeostasis
GO:0070653	high-density lipoprotein particle receptor binding