Gene basic information
| LiverAtlas Gene ID |
HuLG000260 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
FASLG |
|
Synonyms |
APT1LG1|CD178|CD95NL|CD95L|FASL|TNFSF6 |
|
Gene name |
Fas ligand (TNF superfamily, member 6) |
|
Gene Type |
protein-coding |
|
Chromosome |
1 |
|
Genomics Location |
1q23 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:11936
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0005102 |
receptor binding |
|
GO:0005125 |
cytokine activity |
|
GO:0005164 |
tumor necrosis factor receptor binding |
|
GO:0005515 |
protein binding |
|
GO:0005576 |
extracellular region |
|
GO:0005615 |
extracellular space |
|
GO:0005886 |
plasma membrane |
|
GO:0005887 |
integral to plasma membrane |
|
GO:0005901 |
caveola |
|
GO:0006915 |
apoptosis |
|
GO:0006917 |
induction of apoptosis |
|
GO:0006919 |
activation of caspase activity |
|
GO:0006925 |
inflammatory cell apoptosis |
|
GO:0006955 |
immune response |
|
GO:0007165 |
signal transduction |
|
GO:0007267 |
cell-cell signaling |
|
GO:0008284 |
positive regulation of cell proliferation |
|
GO:0008624 |
induction of apoptosis by extracellular signals |
|
GO:0008625 |
induction of apoptosis via death domain receptors |
|
GO:0008633 |
activation of pro-apoptotic gene products |
|
GO:0009897 |
external side of plasma membrane |
|
GO:0016023 |
cytoplasmic membrane-bounded vesicle |
|
GO:0016525 |
negative regulation of angiogenesis |
|
GO:0030644 |
cellular chloride ion homeostasis |
|
GO:0032496 |
response to lipopolysaccharide |
|
GO:0033554 |
cellular response to stress |
|
GO:0043065 |
positive regulation of apoptosis |
|
GO:0043123 |
positive regulation of I-kappaB kinase/NF-kappaB cascade |
|
GO:0043525 |
positive regulation of neuron apoptosis |
|
GO:0045742 |
positive regulation of epidermal growth factor receptor signaling pathway |
|
GO:0046666 |
retinal cell programmed cell death |
|
GO:0048388 |
endosomal lumen acidification |
|
GO:0048471 |
perinuclear region of cytoplasm |
|
GO:0060554 |
induction of necroptosis of activated-T cells |
|
GO:0060555 |
induction of necroptosis by extracellular signals |
|
GO:0070265 |
necrotic cell death |
|
GO:0070848 |
response to growth factor stimulus |
