HuLG000262

Entrez Gene ID

358

Official Gene Symbol

AQP1

Synonyms

AQPNCHIP|CHIP28|CO|MGC26324

Gene name

aquaporin 1 (Colton blood group)

Gene Type

protein-coding

Chromosome

7

Genomics Location

7p14

Protein products

Aquaporin-1

Huntingtin interacting protein 2, isoform CRA a

Aquaporin 1

Uncharacterized protein

Uncharacterized protein

Related liver disease name

Liver fibrosis and liver cirrhosis

Hepatocellular carcinoma

Database cross reference

HGNC:633
MIM:107776
Ensembl:ENSG00000240583
HPRD:00140
RefSeq Genomic nucleotide accession:AC_000050
RefSeq Genomic nucleotide gi:89161211

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

GO annotation

GO:0003097

renal water transport

GO:0005223

intracellular cGMP activated cation channel activity

GO:0005267

potassium channel activity

GO:0005372

water transmembrane transporter activity

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005737

cytoplasm

GO:0005886

plasma membrane

GO:0005887

integral to plasma membrane

GO:0005903

brush border

GO:0006182

cGMP biosynthetic process

GO:0006813

potassium ion transport

GO:0006833

water transport

GO:0006884

cell volume homeostasis

GO:0009925

basal plasma membrane

GO:0015079

potassium ion transmembrane transporter activity

GO:0015168

glycerol transmembrane transporter activity

GO:0015250

water channel activity

GO:0015670

carbon dioxide transport

GO:0015696

ammonium transport

GO:0015793

glycerol transport

GO:0016323

basolateral plasma membrane

GO:0016324

apical plasma membrane

GO:0019725

cellular homeostasis

GO:0020003

symbiont-containing vacuole

GO:0020005

symbiont-containing vacuole membrane

GO:0021670

lateral ventricle development

GO:0022857

transmembrane transporter activity

GO:0030157

pancreatic juice secretion

GO:0030184

nitric oxide transmembrane transporter activity

GO:0030185

nitric oxide transport

GO:0030950

establishment or maintenance of actin cytoskeleton polarity

GO:0031526

brush border membrane

GO:0031965

nuclear membrane

GO:0033326

cerebrospinal fluid secretion

GO:0033554

cellular response to stress

GO:0034644

cellular response to UV

GO:0035377

transepithelial water transport

GO:0035378

carbon dioxide transmembrane transport

GO:0035379

carbon dioxide transmembrane transporter activity

GO:0042383

sarcolemma

GO:0042476

odontogenesis

GO:0042493

response to drug

GO:0043066

negative regulation of apoptosis

GO:0045177

apical part of cell

GO:0045766

positive regulation of angiogenesis

GO:0046878

positive regulation of saliva secretion

GO:0048146

positive regulation of fibroblast proliferation

GO:0050891

multicellular organismal water homeostasis

GO:0051739

ammonia transmembrane transporter activity

GO:0055085

transmembrane transport

GO:0070301

cellular response to hydrogen peroxide

GO:0071241

cellular response to inorganic substance

GO:0071260

cellular response to mechanical stimulus

GO:0071280

cellular response to copper ion

GO:0071288

cellular response to mercury ion

GO:0071300

cellular response to retinoic acid

GO:0071320

cellular response to cAMP

GO:0071456

cellular response to hypoxia

GO:0071472

cellular response to salt stress

GO:0071474

cellular hyperosmotic response

GO:0071549

cellular response to dexamethasone stimulus

GO:0071732

cellular response to nitric oxide

GO:0071805

potassium ion transmembrane transport

GO:0085018

maintenance of symbiont-containing vacuole via substance secreted by host