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Gene basic information

LiverAtlas Gene ID

HuLG000263

Entrez Gene ID

359

Official Gene Symbol

AQP2

Synonyms

AQPNCD|MGC34501|WCHNCD

Gene name

aquaporin 2 (collecting duct)

Gene Type

protein-coding

Chromosome

12

Genomics Location

12q12-q13

Known cancer genes

Yes

Protein products

Aquaporin-2

AQP2 protein

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Viral hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Chronic hepatitis C

Hepatitis D

Hepatitis E

Chronic hepatitis

Database cross reference

HGNC:634
MIM:107777
Ensembl:ENSG00000167580
HPRD:00141
RefSeq Genomic nucleotide accession:AC_000055
RefSeq Genomic nucleotide gi:89161189

 

Ontology annotation

GO ID

GO annotation

GO:0000267

cell fraction

GO:0003097

renal water transport

GO:0003779

actin binding

GO:0005215

transporter activity

GO:0005372

water transmembrane transporter activity

GO:0005624

membrane fraction

GO:0005737

cytoplasm

GO:0005764

lysosome

GO:0005769

early endosome

GO:0005791

rough endoplasmic reticulum

GO:0005802

trans-Golgi network

GO:0005886

plasma membrane

GO:0006833

water transport

GO:0006884

cell volume homeostasis

GO:0006915

apoptosis

GO:0006972

hyperosmotic response

GO:0007565

female pregnancy

GO:0007568

aging

GO:0007588

excretion

GO:0009651

response to salt stress

GO:0009725

response to hormone stimulus

GO:0010226

response to lithium ion

GO:0015168

glycerol transmembrane transporter activity

GO:0015250

water channel activity

GO:0015793

glycerol transport

GO:0016021

integral to membrane

GO:0016323

basolateral plasma membrane

GO:0016324

apical plasma membrane

GO:0030042

actin filament depolymerization

GO:0030136

clathrin-coated vesicle

GO:0030165

PDZ domain binding

GO:0030658

transport vesicle membrane

GO:0031410

cytoplasmic vesicle

GO:0032496

response to lipopolysaccharide

GO:0033762

response to glucagon stimulus

GO:0042594

response to starvation

GO:0042631

cellular response to water deprivation

GO:0043234

protein complex

GO:0051592

response to calcium ion

GO:0051928

positive regulation of calcium ion transport

GO:0055037

recycling endosome

GO:0055085

transmembrane transport

GO:0070382

exocytic vesicle

GO:0071280

cellular response to copper ion

GO:0071288

cellular response to mercury ion

GO:0072205

metanephric collecting duct development