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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000265

Entrez Gene ID

361

Official Gene Symbol

AQP4

Synonyms

HMIWC2|MGC22454|MIWC

Gene name

aquaporin 4

Gene Type

protein-coding

Chromosome

18

Genomics Location

18q11.2-q12.1

Protein products

Aquaporin-4

Aquaporin 4 transcript variant a

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:637
MIM:600308
Ensembl:ENSG00000171885
HPRD:02631
RefSeq Genomic nucleotide accession:AC_000061
RefSeq Genomic nucleotide gi:89161196

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0005215

transporter activity

GO:0005372

water transmembrane transporter activity

GO:0005737

cytoplasm

GO:0005886

plasma membrane

GO:0005887

integral to plasma membrane

GO:0005911

cell-cell junction

GO:0006810

transport

GO:0006833

water transport

GO:0007399

nervous system development

GO:0007588

excretion

GO:0007605

sensory perception of sound

GO:0009897

external side of plasma membrane

GO:0015250

water channel activity

GO:0016323

basolateral plasma membrane

GO:0050891

multicellular organismal water homeostasis

GO:0055085

transmembrane transport

GO:0070295

renal water absorption

GO:0071346

cellular response to interferon-gamma