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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000270

Entrez Gene ID

367

Official Gene Symbol

AR

Synonyms

AIS|DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM

Gene name

androgen receptor

Gene Type

protein-coding

Chromosome

0

Genomics Location

Xq12

Known cancer genes

Yes

Protein products

Androgen receptor

Androgen receptor isoform 1 transcript variant 1

Androgen receptor isoform 1 transcript variant 1

Androgen receptor isoform 1 transcript variant 1

Androgen receptor isoform 1 transcript variant 1

Androgen receptor isoform 1 transcript variant 1

Androgen receptor isoform 1 transcript variant 1

Androgen nuclear receptor variant 2

Androgen receptor

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:644
MIM:313700
Ensembl:ENSG00000169083
HPRD:02437
RefSeq Genomic nucleotide accession:AC_000066
RefSeq Genomic nucleotide gi:89161217

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000790

nuclear chromatin

GO:0001701

in utero embryonic development

GO:0003677

DNA binding

GO:0003700

sequence-specific DNA binding transcription factor activity

GO:0003706

ligand-regulated transcription factor activity

GO:0004872

receptor activity

GO:0004882

androgen receptor activity

GO:0005102

receptor binding

GO:0005497

androgen binding

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005654

nucleoplasm

GO:0005737

cytoplasm

GO:0006351

transcription, DNA-dependent

GO:0006810

transport

GO:0007165

signal transduction

GO:0007267

cell-cell signaling

GO:0007548

sex differentiation

GO:0008013

beta-catenin binding

GO:0008134

transcription factor binding

GO:0008219

cell death

GO:0008270

zinc ion binding

GO:0008283

cell proliferation

GO:0008284

positive regulation of cell proliferation

GO:0008584

male gonad development

GO:0010467

gene expression

GO:0016049

cell growth

GO:0019102

male somatic sex determination

GO:0019899

enzyme binding

GO:0030424

axon

GO:0030425

dendrite

GO:0030521

androgen receptor signaling pathway

GO:0030850

prostate gland development

GO:0032868

response to insulin stimulus

GO:0033148

positive regulation of estrogen receptor signaling pathway

GO:0034339

regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor

GO:0042327

positive regulation of phosphorylation

GO:0043066

negative regulation of apoptosis

GO:0043410

positive regulation of MAPKKK cascade

GO:0043565

sequence-specific DNA binding

GO:0043568

positive regulation of insulin-like growth factor receptor signaling pathway

GO:0045720

negative regulation of integrin biosynthetic process

GO:0045726

positive regulation of integrin biosynthetic process

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

GO:0045945

positive regulation of transcription from RNA polymerase III promoter

GO:0046661

male sex differentiation

GO:0046872

metal ion binding

GO:0046983

protein dimerization activity

GO:0048638

regulation of developmental growth

GO:0048645

organ formation

GO:0048808

male genitalia morphogenesis

GO:0050680

negative regulation of epithelial cell proliferation

GO:0050681

androgen receptor binding

GO:0050790

regulation of catalytic activity

GO:0051092

positive regulation of NF-kappaB transcription factor activity

GO:0060520

activation of prostate induction by androgen receptor signaling pathway

GO:0060571

morphogenesis of an epithelial fold

GO:0060599

lateral sprouting involved in mammary gland duct morphogenesis

GO:0060685

regulation of prostatic bud formation

GO:0060736

prostate gland growth

GO:0060740

prostate gland epithelium morphogenesis

GO:0060742

epithelial cell differentiation involved in prostate gland development

GO:0060748

tertiary branching involved in mammary gland duct morphogenesis

GO:0060749

mammary gland alveolus development

GO:0070974

POU domain binding

GO:0090003

regulation of establishment of protein localization in plasma membrane