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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000282

Entrez Gene ID

383

Official Gene Symbol

ARG1

Gene name

arginase, liver

Gene Type

protein-coding

Chromosome

6

Genomics Location

6q23

Known cancer genes

Yes

Protein products

Arginase-1

Related liver disease name

Hepatitis C

Chronic hepatitis

Autoimmune hepatitis

Hepatocellular carcinoma

Database cross reference

HGNC:663
MIM:608313
Ensembl:ENSG00000118520
HPRD:01947
RefSeq Genomic nucleotide accession:AC_000049
RefSeq Genomic nucleotide gi:89161209

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000050

urea cycle

GO:0001889

liver development

GO:0001938

positive regulation of endothelial cell proliferation

GO:0004053

arginase activity

GO:0005615

extracellular space

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0006527

arginine catabolic process

GO:0009635

response to herbicide

GO:0010042

response to manganese ion

GO:0010043

response to zinc ion

GO:0010269

response to selenium ion

GO:0010963

regulation of L-arginine import

GO:0016787

hydrolase activity

GO:0030145

manganese ion binding

GO:0030324

lung development

GO:0032964

collagen biosynthetic process

GO:0033189

response to vitamin A

GO:0033197

response to vitamin E

GO:0034641

cellular nitrogen compound metabolic process

GO:0042493

response to drug

GO:0043005

neuron projection

GO:0043025

neuronal cell body

GO:0043200

response to amino acid stimulus

GO:0043434

response to peptide hormone stimulus

GO:0046686

response to cadmium ion

GO:0046872

metal ion binding

GO:0048545

response to steroid hormone stimulus

GO:0048678

response to axon injury

GO:0051597

response to methylmercury

GO:0051789

response to protein stimulus

GO:0060056

mammary gland involution

GO:0060135

maternal process involved in female pregnancy

GO:0070207

protein homotrimerization

GO:0070301

cellular response to hydrogen peroxide

GO:0071222

cellular response to lipopolysaccharide

GO:0071377

cellular response to glucagon stimulus

GO:0071549

cellular response to dexamethasone stimulus

GO:0071560

cellular response to transforming growth factor beta stimulus