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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000284

Entrez Gene ID

387

Official Gene Symbol

RHOA

Synonyms

ARH12|ARHA|RHO12|RHOH12

Gene name

ras homolog gene family, member A

Gene Type

protein-coding

Chromosome

3

Genomics Location

3p21.3

Known cancer genes

Yes

Protein products

ARHA protein

Transforming protein RhoA

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:667
MIM:165390
Ensembl:ENSG00000067560
HPRD:01323
RefSeq Genomic nucleotide accession:AC_000046
RefSeq Genomic nucleotide gi:89161204

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0000902

cell morphogenesis

GO:0003924

GTPase activity

GO:0005515

protein binding

GO:0005525

GTP binding

GO:0005622

intracellular

GO:0005634

nucleus

GO:0005737

cytoplasm

GO:0005739

mitochondrion

GO:0005829

cytosol

GO:0005856

cytoskeleton

GO:0005886

plasma membrane

GO:0006184

GTP catabolic process

GO:0006357

regulation of transcription from RNA polymerase II promoter

GO:0007155

cell adhesion

GO:0007160

cell-matrix adhesion

GO:0007264

small GTPase mediated signal transduction

GO:0007266

Rho protein signal transduction

GO:0007411

axon guidance

GO:0007519

skeletal muscle tissue development

GO:0007596

blood coagulation

GO:0017022

myosin binding

GO:0030036

actin cytoskeleton organization

GO:0030154

cell differentiation

GO:0030168

platelet activation

GO:0030334

regulation of cell migration

GO:0030521

androgen receptor signaling pathway

GO:0033144

negative regulation of steroid hormone receptor signaling pathway

GO:0042346

positive regulation of NF-kappaB import into nucleus

GO:0043123

positive regulation of I-kappaB kinase/NF-kappaB cascade

GO:0043524

negative regulation of neuron apoptosis

GO:0044419

interspecies interaction between organisms

GO:0045666

positive regulation of neuron differentiation

GO:0048011

nerve growth factor receptor signaling pathway

GO:0048015

phosphatidylinositol-mediated signaling

GO:0050770

regulation of axonogenesis

GO:0050771

negative regulation of axonogenesis

GO:0050772

positive regulation of axonogenesis

GO:0051056

regulation of small GTPase mediated signal transduction

GO:0051496

positive regulation of stress fiber assembly