HuLG000285

Entrez Gene ID

388

Official Gene Symbol

RHOB

Synonyms

ARH6|ARHB|MST081|MSTP081|RHOH6

Gene name

ras homolog gene family, member B

Gene Type

protein-coding

Chromosome

2

Genomics Location

2p24

Known cancer genes

Yes

Protein products

Salt-tolerant protein

Ras homolog gene family, member B, isoform CRA a

Rho-related GTP-binding protein RhoB

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:668
MIM:165370
Ensembl:ENSG00000143878
HPRD:01321
RefSeq Genomic nucleotide accession:AC_000045
RefSeq Genomic nucleotide gi:89161198

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

GO annotation

GO:0000166

nucleotide binding

GO:0003924

GTPase activity

GO:0005515

protein binding

GO:0005525

GTP binding

GO:0005622

intracellular

GO:0005624

membrane fraction

GO:0005625

soluble fraction

GO:0005634

nucleus

GO:0005768

endosome

GO:0005829

cytosol

GO:0005886

plasma membrane

GO:0006184

GTP catabolic process

GO:0006915

apoptosis

GO:0006927

transformed cell apoptosis

GO:0007155

cell adhesion

GO:0007264

small GTPase mediated signal transduction

GO:0007266

Rho protein signal transduction

GO:0007275

multicellular organismal development

GO:0007411

axon guidance

GO:0007596

blood coagulation

GO:0008333

endosome to lysosome transport

GO:0010008

endosome membrane

GO:0015031

protein transport

GO:0019003

GDP binding

GO:0030154

cell differentiation

GO:0030168

platelet activation

GO:0031902

late endosome membrane

GO:0045766

positive regulation of angiogenesis

GO:0045786

negative regulation of cell cycle

GO:0051056

regulation of small GTPase mediated signal transduction