Choose one of the five choices you want to search:

Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000300

Entrez Gene ID

405

Official Gene Symbol

ARNT

Synonyms

HIFN1Nbeta|HIFN1beta|HIF1Nbeta|HIF1B|HIF1BETA|TANGO|bHLHe2

Gene name

aryl hydrocarbon receptor nuclear translocator

Gene Type

protein-coding

Chromosome

1

Genomics Location

1q21

Known cancer genes

Yes

Protein products

cDNA FLJ75039, highly similar to Homo sapiens aryl hydrocarbon receptor nuclear translocator (ARNT), transcript variant 3, mRNA

Aryl hydrocarbon receptor nuclear translocator

cDNA, FLJ79461, highly similar to Aryl hydrocarbon receptor nuclear translocator

Beta 2-microglobulin protein

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:700
MIM:126110
Ensembl:ENSG00000143437
HPRD:00524
RefSeq Genomic nucleotide accession:AC_000044
RefSeq Genomic nucleotide gi:89161184

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0001666

response to hypoxia

GO:0001892

embryonic placenta development

GO:0001938

positive regulation of endothelial cell proliferation

GO:0003700

sequence-specific DNA binding transcription factor activity

GO:0003705

sequence-specific enhancer binding RNA polymerase II transcription factor activity

GO:0003713

transcription coactivator activity

GO:0004871

signal transducer activity

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005667

transcription factor complex

GO:0005737

cytoplasm

GO:0006351

transcription, DNA-dependent

GO:0008134

transcription factor binding

GO:0010575

positive regulation vascular endothelial growth factor production

GO:0017162

aryl hydrocarbon receptor binding

GO:0030154

cell differentiation

GO:0030949

positive regulation of vascular endothelial growth factor receptor signaling pathway

GO:0033235

positive regulation of protein sumoylation

GO:0042789

mRNA transcription from RNA polymerase II promoter

GO:0043565

sequence-specific DNA binding

GO:0043619

regulation of transcription from RNA polymerase II promoter in response to oxidative stress

GO:0045648

positive regulation of erythrocyte differentiation

GO:0045821

positive regulation of glycolysis

GO:0045893

positive regulation of transcription, DNA-dependent

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

GO:0046886

positive regulation of hormone biosynthetic process

GO:0046982

protein heterodimerization activity