Gene basic information
LiverAtlas Gene ID |
HuLG000316 |
Entrez Gene ID |
|
Official Gene Symbol |
ASCL1 |
Synonyms |
ASH1|HASH1|MASH1|bHLHa46 |
Gene name |
achaete-scute complex homolog 1 (Drosophila) |
Gene Type |
protein-coding |
Chromosome |
12 |
Genomics Location |
12q23.2 |
Known cancer genes |
Yes |
Protein products |
|
Related liver disease name |
|
Database cross reference |
HGNC:738
|
Liver relevance
HCC significant genes |
Yes/No |
Yes |
Evidence |
HCC.net |
|
Quality score |
|
Ontology annotation
GO ID |
GO annotation |
GO:0001764 |
neuron migration |
GO:0003359 |
noradrenergic neuron fate commitment |
GO:0003690 |
double-stranded DNA binding |
GO:0003700 |
sequence-specific DNA binding transcription factor activity |
GO:0005515 |
protein binding |
GO:0005634 |
nucleus |
GO:0006351 |
transcription, DNA-dependent |
GO:0007219 |
Notch signaling pathway |
GO:0007389 |
pattern specification process |
GO:0007400 |
neuroblast fate determination |
GO:0007405 |
neuroblast proliferation |
GO:0010226 |
response to lithium ion |
GO:0014003 |
oligodendrocyte development |
GO:0021527 |
spinal cord association neuron differentiation |
GO:0021530 |
spinal cord oligodendrocyte cell fate specification |
GO:0021779 |
oligodendrocyte cell fate commitment |
GO:0021879 |
forebrain neuron differentiation |
GO:0021892 |
cerebral cortex GABAergic interneuron differentiation |
GO:0021954 |
central nervous system neuron development |
GO:0021987 |
cerebral cortex development |
GO:0022008 |
neurogenesis |
GO:0032526 |
response to retinoic acid |
GO:0042803 |
protein homodimerization activity |
GO:0043025 |
neuronal cell body |
GO:0043066 |
negative regulation of apoptosis |
GO:0043425 |
bHLH transcription factor binding |
GO:0043525 |
positive regulation of neuron apoptosis |
GO:0043565 |
sequence-specific DNA binding |
GO:0045665 |
negative regulation of neuron differentiation |
GO:0045666 |
positive regulation of neuron differentiation |
GO:0045747 |
positive regulation of Notch signaling pathway |
GO:0045892 |
negative regulation of transcription, DNA-dependent |
GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
GO:0048485 |
sympathetic nervous system development |
GO:0048665 |
neuron fate specification |
GO:0050769 |
positive regulation of neurogenesis |
GO:0051593 |
response to folic acid |
GO:0060163 |
subpallium neuron fate commitment |
GO:0060165 |
regulation of timing of subpallium neuron differentiation |
GO:0060166 |
olfactory pit development |
GO:0060487 |
lung epithelial cell differentiation |
GO:0061100 |
lung neuroendocrine cell differentiation |
GO:0061102 |
stomach neuroendocrine cell differentiation |
GO:0061103 |
carotid body glomus cell differentiation |
GO:0061104 |
adrenal chromaffin cell differentiation |
GO:0070849 |
response to epidermal growth factor stimulus |
GO:0070888 |
E-box binding |
GO:0071259 |
cellular response to magnetism |