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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000329

Entrez Gene ID

462

Official Gene Symbol

SERPINC1

Synonyms

AT3|ATIII|MGC22579

Gene name

serpin peptidase inhibitor, clade C (antithrombin), member 1

Gene Type

protein-coding

Chromosome

1

Genomics Location

1q23-q25.1

Known cancer genes

Yes

Protein products

Antithrombin-III

Antithrombin

Antithrombin

Antithrombin

Antithrombin

SERPINC1 protein

Antithrombin III

Related liver disease name

Liver fibrosis and liver cirrhosis

Hepatocellular carcinoma

Intrahepatic cholangiocarcinoma

Database cross reference

HGNC:775
MIM:107300
Ensembl:ENSG00000117601
HPRD:00122
RefSeq Genomic nucleotide accession:AC_000044
RefSeq Genomic nucleotide gi:89161184

Liver relevance

Liver sepcificity

Yes/No

Yes

Evidence

BodyMap

Quality score

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0002020

protease binding

GO:0004867

serine-type endopeptidase inhibitor activity

GO:0005515

protein binding

GO:0005576

extracellular region

GO:0005615

extracellular space

GO:0005886

plasma membrane

GO:0007584

response to nutrient

GO:0007596

blood coagulation

GO:0008201

heparin binding

GO:0010951

negative regulation of endopeptidase activity

GO:0030162

regulation of proteolysis

GO:0030414

peptidase inhibitor activity

GO:0050728

negative regulation of inflammatory response