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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000331

Entrez Gene ID

466

Official Gene Symbol

ATF1

Synonyms

EWSNATF1|FUS/ATFN1|TREB36

Gene name

activating transcription factor 1

Gene Type

protein-coding

Chromosome

12

Genomics Location

12q13

Known cancer genes

Yes

Protein products

Cyclic AMP-dependent transcription factor ATF-1

Urokinase-type plasminogen activator amino-terminal

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:783
MIM:123803
Ensembl:ENSG00000123268
HPRD:00440
RefSeq Genomic nucleotide accession:AC_000055
RefSeq Genomic nucleotide gi:89161189

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0002224

toll-like receptor signaling pathway

GO:0002755

MyD88-dependent toll-like receptor signaling pathway

GO:0002756

MyD88-independent toll-like receptor signaling pathway

GO:0003700

sequence-specific DNA binding transcription factor activity

GO:0003705

sequence-specific enhancer binding RNA polymerase II transcription factor activity

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005654

nucleoplasm

GO:0005667

transcription factor complex

GO:0006351

transcription, DNA-dependent

GO:0006355

regulation of transcription, DNA-dependent

GO:0008063

Toll signaling pathway

GO:0010976

positive regulation of neuron projection development

GO:0014070

response to organic cyclic compound

GO:0032025

response to cobalt ion

GO:0032403

protein complex binding

GO:0034130

toll-like receptor 1 signaling pathway

GO:0034134

toll-like receptor 2 signaling pathway

GO:0034138

toll-like receptor 3 signaling pathway

GO:0034142

toll-like receptor 4 signaling pathway

GO:0043565

sequence-specific DNA binding

GO:0043623

cellular protein complex assembly

GO:0045087

innate immune response

GO:0045740

positive regulation of DNA replication

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

GO:0046982

protein heterodimerization activity

GO:0048011

nerve growth factor receptor signaling pathway

GO:0051403

stress-activated MAPK cascade