Gene basic information
| LiverAtlas Gene ID |
HuLG000334 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
ATIC |
|
Synonyms |
AICAR|AICARFT|FLJ93545|IMPCHASE|PURH |
|
Gene name |
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase |
|
Gene Type |
protein-coding |
|
Chromosome |
2 |
|
Genomics Location |
2q35 |
|
Known cancer genes |
Yes |
|
Protein products |
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase, isoform CRA g |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:794
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0003937 |
IMP cyclohydrolase activity |
|
GO:0004643 |
phosphoribosylaminoimidazolecarboxamide formyltransferase activity |
|
GO:0005515 |
protein binding |
|
GO:0005739 |
mitochondrion |
|
GO:0005829 |
cytosol |
|
GO:0006139 |
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process |
|
GO:0006144 |
purine base metabolic process |
|
GO:0006164 |
purine nucleotide biosynthetic process |
|
GO:0006188 |
IMP biosynthetic process |
|
GO:0009168 |
purine ribonucleoside monophosphate biosynthetic process |
|
GO:0016740 |
transferase activity |
|
GO:0016787 |
hydrolase activity |
|
GO:0031100 |
organ regeneration |
|
GO:0042803 |
protein homodimerization activity |
|
GO:0055086 |
nucleobase, nucleoside and nucleotide metabolic process |
