Gene basic information
| LiverAtlas Gene ID |
HuLG000339 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
ATP1A1 |
|
Synonyms |
MGC3285|MGC51750 |
|
Gene name |
ATPase, Na+/K+ transporting, alpha 1 polypeptide |
|
Gene Type |
protein-coding |
|
Chromosome |
1 |
|
Genomics Location |
1p21 |
|
Known cancer genes |
Yes |
|
Protein products |
Sodium/potassium-transporting ATPase subunit alpha-1 cDNA FLJ55427, highly similar to Sodium/potassium-transporting ATPase alpha-1 chain (EC 3.6.3.9) ATPase, Na+/K+ transporting, alpha 1 polypeptide, isoform CRA a Na+/K+ transporting ATPase alpha 1 polypeptide ATPase, Na+/K+ transporting, alpha 1 polypeptide |
|
Database cross reference |
HGNC:799
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000166 |
nucleotide binding |
|
GO:0002026 |
regulation of the force of heart contraction |
|
GO:0003869 |
4-nitrophenylphosphatase activity |
|
GO:0005391 |
sodium:potassium-exchanging ATPase activity |
|
GO:0005515 |
protein binding |
|
GO:0005524 |
ATP binding |
|
GO:0005624 |
membrane fraction |
|
GO:0005792 |
microsome |
|
GO:0005886 |
plasma membrane |
|
GO:0005890 |
sodium:potassium-exchanging ATPase complex |
|
GO:0006754 |
ATP biosynthetic process |
|
GO:0006813 |
potassium ion transport |
|
GO:0006814 |
sodium ion transport |
|
GO:0008217 |
regulation of blood pressure |
|
GO:0015077 |
monovalent inorganic cation transmembrane transporter activity |
|
GO:0015662 |
ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism |
|
GO:0016021 |
integral to membrane |
|
GO:0016323 |
basolateral plasma membrane |
|
GO:0016787 |
hydrolase activity |
|
GO:0016820 |
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances |
|
GO:0031947 |
negative regulation of glucocorticoid biosynthetic process |
|
GO:0034220 |
ion transmembrane transport |
|
GO:0042383 |
sarcolemma |
|
GO:0042470 |
melanosome |
|
GO:0042493 |
response to drug |
|
GO:0045822 |
negative regulation of heart contraction |
|
GO:0045823 |
positive regulation of heart contraction |
|
GO:0045989 |
positive regulation of striated muscle contraction |
|
GO:0046872 |
metal ion binding |
|
GO:0055085 |
transmembrane transport |
