HuLG000355

Entrez Gene ID

495

Official Gene Symbol

ATP4A

Synonyms

ATP6A

Gene name

ATPase, H+/K+ exchanging, alpha polypeptide

Gene Type

protein-coding

Chromosome

19

Genomics Location

19q13.1

Known cancer genes

Yes

Protein products

Potassium-transporting ATPase alpha chain 1

Putative uncharacterized protein DKFZp666G172

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:819
MIM:137216
Ensembl:ENSG00000105675
HPRD:00668
RefSeq Genomic nucleotide accession:AC_000062
RefSeq Genomic nucleotide gi:89161197

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

GO annotation

GO:0000166

nucleotide binding

GO:0000287

magnesium ion binding

GO:0005524

ATP binding

GO:0005886

plasma membrane

GO:0005887

integral to plasma membrane

GO:0006754

ATP biosynthetic process

GO:0006810

transport

GO:0006813

potassium ion transport

GO:0008900

hydrogen:potassium-exchanging ATPase activity

GO:0015077

monovalent inorganic cation transmembrane transporter activity

GO:0015662

ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism

GO:0015991

ATP hydrolysis coupled proton transport

GO:0015992

proton transport

GO:0016324

apical plasma membrane

GO:0016787

hydrolase activity

GO:0016820

hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances

GO:0034220

ion transmembrane transport

GO:0055085

transmembrane transport