HuLG000371

Entrez Gene ID

526

Official Gene Symbol

ATP6V1B2

Synonyms

ATP6B1B2|ATP6B2|HO57|VATB|VPP3|Vma2

Gene name

ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2

Gene Type

protein-coding

Chromosome

8

Genomics Location

8p21.3

Protein products

V-type proton ATPase subunit B, brain isoform

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:854
MIM:606939
Ensembl:ENSG00000147416
HPRD:06088
RefSeq Genomic nucleotide accession:AC_000051
RefSeq Genomic nucleotide gi:89161214

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

GO annotation

GO:0005524

ATP binding

GO:0005794

Golgi apparatus

GO:0005829

cytosol

GO:0005886

plasma membrane

GO:0006811

ion transport

GO:0006879

cellular iron ion homeostasis

GO:0008286

insulin receptor signaling pathway

GO:0012505

endomembrane system

GO:0015078

hydrogen ion transmembrane transporter activity

GO:0015991

ATP hydrolysis coupled proton transport

GO:0015992

proton transport

GO:0016021

integral to membrane

GO:0016787

hydrolase activity

GO:0016820

hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances

GO:0033180

proton-transporting V-type ATPase, V1 domain

GO:0033572

transferrin transport

GO:0042470

melanosome

GO:0043231

intracellular membrane-bounded organelle

GO:0046034

ATP metabolic process

GO:0046933

hydrogen ion transporting ATP synthase activity, rotational mechanism

GO:0046961

proton-transporting ATPase activity, rotational mechanism

GO:0055085

transmembrane transport