Gene basic information
| LiverAtlas Gene ID |
HuLG000382 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
ATR |
|
Synonyms |
FRP1|MEC1|SCKL|SCKL1 |
|
Gene name |
ataxia telangiectasia and Rad3 related |
|
Gene Type |
protein-coding |
|
Chromosome |
3 |
|
Genomics Location |
3q22-q24 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:882
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000075 |
cell cycle checkpoint |
|
GO:0000077 |
DNA damage checkpoint |
|
GO:0000166 |
nucleotide binding |
|
GO:0001741 |
XY body |
|
GO:0003677 |
DNA binding |
|
GO:0004672 |
protein kinase activity |
|
GO:0004674 |
protein serine/threonine kinase activity |
|
GO:0005515 |
protein binding |
|
GO:0005524 |
ATP binding |
|
GO:0005634 |
nucleus |
|
GO:0005654 |
nucleoplasm |
|
GO:0006260 |
DNA replication |
|
GO:0006281 |
DNA repair |
|
GO:0006974 |
response to DNA damage stimulus |
|
GO:0007049 |
cell cycle |
|
GO:0007275 |
multicellular organismal development |
|
GO:0008156 |
negative regulation of DNA replication |
|
GO:0016605 |
PML body |
|
GO:0018105 |
peptidyl-serine phosphorylation |
|
GO:0032405 |
MutLalpha complex binding |
|
GO:0032407 |
MutSalpha complex binding |
|
GO:0034644 |
cellular response to UV |
|
GO:0043393 |
regulation of protein binding |
|
GO:0043517 |
positive regulation of DNA damage response, signal transduction by p53 class mediator |
|
GO:0046777 |
protein autophosphorylation |
|
GO:0071480 |
cellular response to gamma radiation |
|
GO:0090399 |
replicative senescence |
