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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000391

Entrez Gene ID

558

Official Gene Symbol

AXL

Synonyms

JTK11|UFO

Gene name

AXL receptor tyrosine kinase

Gene Type

protein-coding

Chromosome

19

Genomics Location

19q13.1

Known cancer genes

Yes

Protein products

Tyrosine-protein kinase receptor UFO

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:905
MIM:109135
Ensembl:ENSG00000167601
HPRD:00171
RefSeq Genomic nucleotide accession:AC_000062
RefSeq Genomic nucleotide gi:89161197

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0001764

neuron migration

GO:0001779

natural killer cell differentiation

GO:0001974

blood vessel remodeling

GO:0004714

transmembrane receptor protein tyrosine kinase activity

GO:0004872

receptor activity

GO:0005524

ATP binding

GO:0005887

integral to plasma membrane

GO:0006468

protein phosphorylation

GO:0006954

inflammatory response

GO:0007165

signal transduction

GO:0007167

enzyme linked receptor protein signaling pathway

GO:0007283

spermatogenesis

GO:0016020

membrane

GO:0021885

forebrain cell migration

GO:0030168

platelet activation

GO:0031668

cellular response to extracellular stimulus

GO:0032720

negative regulation of tumor necrosis factor production

GO:0032940

secretion by cell

GO:0034101

erythrocyte homeostasis

GO:0034446

substrate adhesion-dependent cell spreading

GO:0042698

ovulation cycle

GO:0043277

apoptotic cell clearance

GO:0043491

protein kinase B signaling cascade

GO:0043524

negative regulation of neuron apoptosis

GO:0046982

protein heterodimerization activity

GO:0051250

negative regulation of lymphocyte activation

GO:0060068

vagina development