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Gene basic information

LiverAtlas Gene ID

HuLG000420

Entrez Gene ID

602

Official Gene Symbol

BCL3

Synonyms

BCL4|D19S37

Gene name

B-cell CLL/lymphoma 3

Gene Type

protein-coding

Chromosome

19

Genomics Location

19q13.1-q13.2

Known cancer genes

Yes

Protein products

B-cell lymphoma 3 protein

Database cross reference

HGNC:998
MIM:109560
Ensembl:ENSG00000069399
HPRD:00179
RefSeq Genomic nucleotide accession:AC_000062
RefSeq Genomic nucleotide gi:89161197

 

Ontology annotation

GO ID

GO annotation

GO:0000060

protein import into nucleus, translocation

GO:0002268

follicular dendritic cell differentiation

GO:0002315

marginal zone B cell differentiation

GO:0002455

humoral immune response mediated by circulating immunoglobulin

GO:0002467

germinal center formation

GO:0003700

sequence-specific DNA binding transcription factor activity

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005737

cytoplasm

GO:0006974

response to DNA damage stimulus

GO:0007249

I-kappaB kinase/NF-kappaB cascade

GO:0008134

transcription factor binding

GO:0009615

response to virus

GO:0010225

response to UV-C

GO:0019730

antimicrobial humoral response

GO:0030198

extracellular matrix organization

GO:0030330

DNA damage response, signal transduction by p53 class mediator

GO:0030674

protein binding, bridging

GO:0032729

positive regulation of interferon-gamma production

GO:0032996

Bcl3-Bcl10 complex

GO:0033257

Bcl3/NF-kappaB2 complex

GO:0042088

T-helper 1 type immune response

GO:0042345

regulation of NF-kappaB import into nucleus

GO:0042536

negative regulation of tumor necrosis factor biosynthetic process

GO:0042742

defense response to bacterium

GO:0042771

DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis

GO:0042832

defense response to protozoan

GO:0042981

regulation of apoptosis

GO:0043066

negative regulation of apoptosis

GO:0043234

protein complex

GO:0045064

T-helper 2 cell differentiation

GO:0045082

positive regulation of interleukin-10 biosynthetic process

GO:0045415

negative regulation of interleukin-8 biosynthetic process

GO:0045727

positive regulation of translation

GO:0045892

negative regulation of transcription, DNA-dependent

GO:0045893

positive regulation of transcription, DNA-dependent

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

GO:0048471

perinuclear region of cytoplasm

GO:0048536

spleen development

GO:0051101

regulation of DNA binding

GO:0051457

maintenance of protein location in nucleus