Gene basic information
LiverAtlas Gene ID |
HuLG000421 |
Entrez Gene ID |
|
Official Gene Symbol |
BCL6 |
Synonyms |
BCL5|BCL6A|LAZ3|ZBTB27|ZNF51 |
Gene name |
B-cell CLL/lymphoma 6 |
Gene Type |
protein-coding |
Chromosome |
3 |
Genomics Location |
3q27 |
Known cancer genes |
Yes |
Protein products |
Zinc finger transcription factor BCL6S |
Related liver disease name |
|
Database cross reference |
HGNC:1001
|
Ontology annotation
GO ID |
GO annotation |
GO:0000060 |
protein import into nucleus, translocation |
GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
GO:0000902 |
cell morphogenesis |
GO:0001953 |
negative regulation of cell-matrix adhesion |
GO:0002634 |
regulation of germinal center formation |
GO:0002829 |
negative regulation of type 2 immune response |
GO:0002903 |
negative regulation of B cell apoptosis |
GO:0003682 |
chromatin binding |
GO:0003700 |
sequence-specific DNA binding transcription factor activity |
GO:0005515 |
protein binding |
GO:0005622 |
intracellular |
GO:0005634 |
nucleus |
GO:0005657 |
replication fork |
GO:0005730 |
nucleolus |
GO:0006351 |
transcription, DNA-dependent |
GO:0006355 |
regulation of transcription, DNA-dependent |
GO:0006974 |
response to DNA damage stimulus |
GO:0007283 |
spermatogenesis |
GO:0008104 |
protein localization |
GO:0008270 |
zinc ion binding |
GO:0008285 |
negative regulation of cell proliferation |
GO:0030036 |
actin cytoskeleton organization |
GO:0030183 |
B cell differentiation |
GO:0030308 |
negative regulation of cell growth |
GO:0030890 |
positive regulation of B cell proliferation |
GO:0031490 |
chromatin DNA binding |
GO:0032319 |
regulation of Rho GTPase activity |
GO:0032764 |
negative regulation of mast cell cytokine production |
GO:0035024 |
negative regulation of Rho protein signal transduction |
GO:0043065 |
positive regulation of apoptosis |
GO:0043066 |
negative regulation of apoptosis |
GO:0043380 |
regulation of memory T cell differentiation |
GO:0043565 |
sequence-specific DNA binding |
GO:0045596 |
negative regulation of cell differentiation |
GO:0045629 |
negative regulation of T-helper 2 cell differentiation |
GO:0045749 |
negative regulation of S phase of mitotic cell cycle |
GO:0046872 |
metal ion binding |
GO:0048294 |
negative regulation of isotype switching to IgE isotypes |
GO:0048821 |
erythrocyte development |
GO:0050727 |
regulation of inflammatory response |
GO:0050776 |
regulation of immune response |
GO:0051272 |
positive regulation of cellular component movement |