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Gene basic information

LiverAtlas Gene ID

HuLG000421

Entrez Gene ID

604

Official Gene Symbol

BCL6

Synonyms

BCL5|BCL6A|LAZ3|ZBTB27|ZNF51

Gene name

B-cell CLL/lymphoma 6

Gene Type

protein-coding

Chromosome

3

Genomics Location

3q27

Known cancer genes

Yes

Protein products

B-cell CLL/lymphoma 6

Zinc finger transcription factor BCL6S

B-cell lymphoma 6 protein transcript variant

B-cell lymphoma 6 protein

Related liver disease name

Hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Chronic hepatitis C

Hepatitis D

Hepatitis E

Database cross reference

HGNC:1001
MIM:109565
Ensembl:ENSG00000113916
HPRD:00180
RefSeq Genomic nucleotide accession:AC_000046
RefSeq Genomic nucleotide gi:89161204

 

Ontology annotation

GO ID

GO annotation

GO:0000060

protein import into nucleus, translocation

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

GO:0000902

cell morphogenesis

GO:0001953

negative regulation of cell-matrix adhesion

GO:0002634

regulation of germinal center formation

GO:0002829

negative regulation of type 2 immune response

GO:0002903

negative regulation of B cell apoptosis

GO:0003682

chromatin binding

GO:0003700

sequence-specific DNA binding transcription factor activity

GO:0005515

protein binding

GO:0005622

intracellular

GO:0005634

nucleus

GO:0005657

replication fork

GO:0005730

nucleolus

GO:0006351

transcription, DNA-dependent

GO:0006355

regulation of transcription, DNA-dependent

GO:0006974

response to DNA damage stimulus

GO:0007283

spermatogenesis

GO:0008104

protein localization

GO:0008270

zinc ion binding

GO:0008285

negative regulation of cell proliferation

GO:0030036

actin cytoskeleton organization

GO:0030183

B cell differentiation

GO:0030308

negative regulation of cell growth

GO:0030890

positive regulation of B cell proliferation

GO:0031490

chromatin DNA binding

GO:0032319

regulation of Rho GTPase activity

GO:0032764

negative regulation of mast cell cytokine production

GO:0035024

negative regulation of Rho protein signal transduction

GO:0043065

positive regulation of apoptosis

GO:0043066

negative regulation of apoptosis

GO:0043380

regulation of memory T cell differentiation

GO:0043565

sequence-specific DNA binding

GO:0045596

negative regulation of cell differentiation

GO:0045629

negative regulation of T-helper 2 cell differentiation

GO:0045749

negative regulation of S phase of mitotic cell cycle

GO:0046872

metal ion binding

GO:0048294

negative regulation of isotype switching to IgE isotypes

GO:0048821

erythrocyte development

GO:0050727

regulation of inflammatory response

GO:0050776

regulation of immune response

GO:0051272

positive regulation of cellular component movement