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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000449

Entrez Gene ID

648

Official Gene Symbol

BMI1

Synonyms

FLVI2/BMI1|MGC12685|PCGF4|RNF51

Gene name

BMI1 polycomb ring finger oncogene

Gene Type

protein-coding

Chromosome

10

Genomics Location

10p11.23

Known cancer genes

Yes

Protein products

Polycomb complex protein BMI-1

Uncharacterized protein

BMI1 polycomb ring finger oncogene

BMI1 polycomb ring finger oncogene

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:1066
MIM:164831
Ensembl:ENSG00000168283
HPRD:01277
RefSeq Genomic nucleotide accession:AC_000053
RefSeq Genomic nucleotide gi:89161186

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

GO:0000151

ubiquitin ligase complex

GO:0001701

in utero embryonic development

GO:0003682

chromatin binding

GO:0005634

nucleus

GO:0005730

nucleolus

GO:0005737

cytoplasm

GO:0006355

regulation of transcription, DNA-dependent

GO:0006959

humoral immune response

GO:0007379

segment specification

GO:0007420

brain development

GO:0008270

zinc ion binding

GO:0010468

regulation of gene expression

GO:0016568

chromatin modification

GO:0016573

histone acetylation

GO:0016574

histone ubiquitination

GO:0016604

nuclear body

GO:0021903

rostrocaudal neural tube patterning

GO:0030097

hemopoiesis

GO:0030890

positive regulation of B cell proliferation

GO:0031519

PcG protein complex

GO:0033092

positive regulation of immature T cell proliferation in thymus

GO:0043066

negative regulation of apoptosis

GO:0046872

metal ion binding

GO:0048103

somatic stem cell division

GO:0048146

positive regulation of fibroblast proliferation

GO:0048704

embryonic skeletal system morphogenesis

GO:0051443

positive regulation of ubiquitin-protein ligase activity

GO:0071535

RING-like zinc finger domain binding