Gene basic information
| LiverAtlas Gene ID |
HuLG000451 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
BMP2 |
|
Synonyms |
BMP2A |
|
Gene name |
bone morphogenetic protein 2 |
|
Gene Type |
protein-coding |
|
Chromosome |
20 |
|
Genomics Location |
20p12 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:1069
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
|
GO:0001501 |
skeletal system development |
|
GO:0001649 |
osteoblast differentiation |
|
GO:0001658 |
branching involved in ureteric bud morphogenesis |
|
GO:0001666 |
response to hypoxia |
|
GO:0001701 |
in utero embryonic development |
|
GO:0001837 |
epithelial to mesenchymal transition |
|
GO:0001934 |
positive regulation of protein phosphorylation |
|
GO:0001938 |
positive regulation of endothelial cell proliferation |
|
GO:0003130 |
BMP signaling pathway involved in heart induction |
|
GO:0003181 |
atrioventricular valve morphogenesis |
|
GO:0003203 |
endocardial cushion morphogenesis |
|
GO:0004675 |
transmembrane receptor protein serine/threonine kinase activity |
|
GO:0004745 |
retinol dehydrogenase activity |
|
GO:0005102 |
receptor binding |
|
GO:0005125 |
cytokine activity |
|
GO:0005160 |
transforming growth factor beta receptor binding |
|
GO:0005515 |
protein binding |
|
GO:0005576 |
extracellular region |
|
GO:0005615 |
extracellular space |
|
GO:0005737 |
cytoplasm |
|
GO:0006355 |
regulation of transcription, DNA-dependent |
|
GO:0006954 |
inflammatory response |
|
GO:0007219 |
Notch signaling pathway |
|
GO:0007267 |
cell-cell signaling |
|
GO:0008083 |
growth factor activity |
|
GO:0008285 |
negative regulation of cell proliferation |
|
GO:0009612 |
response to mechanical stimulus |
|
GO:0009790 |
embryo development |
|
GO:0009887 |
organ morphogenesis |
|
GO:0010628 |
positive regulation of gene expression |
|
GO:0010718 |
positive regulation of epithelial to mesenchymal transition |
|
GO:0010862 |
positive regulation of pathway-restricted SMAD protein phosphorylation |
|
GO:0010922 |
positive regulation of phosphatase activity |
|
GO:0016362 |
activin receptor activity, type II |
|
GO:0019211 |
phosphatase activator activity |
|
GO:0019904 |
protein domain specific binding |
|
GO:0021537 |
telencephalon development |
|
GO:0021978 |
telencephalon regionalization |
|
GO:0030501 |
positive regulation of bone mineralization |
|
GO:0030509 |
BMP signaling pathway |
|
GO:0031648 |
protein destabilization |
|
GO:0031988 |
membrane-bounded vesicle |
|
GO:0032526 |
response to retinoic acid |
|
GO:0035051 |
cardiac cell differentiation |
|
GO:0035054 |
embryonic heart tube anterior/posterior pattern formation |
|
GO:0035630 |
bone mineralization involved in bone maturation |
|
GO:0040007 |
growth |
|
GO:0042482 |
positive regulation of odontogenesis |
|
GO:0042487 |
regulation of odontogenesis of dentine-containing tooth |
|
GO:0042698 |
ovulation cycle |
|
GO:0042803 |
protein homodimerization activity |
|
GO:0043065 |
positive regulation of apoptosis |
|
GO:0043234 |
protein complex |
|
GO:0045165 |
cell fate commitment |
|
GO:0045666 |
positive regulation of neuron differentiation |
|
GO:0045669 |
positive regulation of osteoblast differentiation |
|
GO:0045778 |
positive regulation of ossification |
|
GO:0045786 |
negative regulation of cell cycle |
|
GO:0045892 |
negative regulation of transcription, DNA-dependent |
|
GO:0045893 |
positive regulation of transcription, DNA-dependent |
|
GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
|
GO:0046332 |
SMAD binding |
|
GO:0046982 |
protein heterodimerization activity |
|
GO:0048711 |
positive regulation of astrocyte differentiation |
|
GO:0048762 |
mesenchymal cell differentiation |
|
GO:0050769 |
positive regulation of neurogenesis |
|
GO:0055008 |
cardiac muscle tissue morphogenesis |
|
GO:0060039 |
pericardium development |
|
GO:0060128 |
corticotropin hormone secreting cell differentiation |
|
GO:0060129 |
thyroid-stimulating hormone-secreting cell differentiation |
|
GO:0060317 |
cardiac epithelial to mesenchymal transition |
|
GO:0060389 |
pathway-restricted SMAD protein phosphorylation |
|
GO:0060395 |
SMAD protein signal transduction |
|
GO:0060804 |
positive regulation of WNT receptor signaling pathway by BMP signaling pathway |
|
GO:0061036 |
positive regulation of cartilage development |
|
GO:0070700 |
BMP receptor binding |
|
GO:0071363 |
cellular response to growth factor stimulus |
|
GO:0071407 |
cellular response to organic cyclic compound |
