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Gene basic information

LiverAtlas Gene ID

HuLG000456

Entrez Gene ID

655

Official Gene Symbol

BMP7

Synonyms

OPN1

Gene name

bone morphogenetic protein 7

Gene Type

protein-coding

Chromosome

20

Genomics Location

20q13

Protein products

Bone morphogenetic protein 7 (Osteogenic protein 1), isoform CRA b

Bone morphogenetic protein 7

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Database cross reference

HGNC:1074
MIM:112267
Ensembl:ENSG00000101144
HPRD:00212
RefSeq Genomic nucleotide accession:AC_000063
RefSeq Genomic nucleotide gi:89161200

 

Ontology annotation

GO ID

GO annotation

GO:0001501

skeletal system development

GO:0001503

ossification

GO:0001654

eye development

GO:0001656

metanephros development

GO:0001657

ureteric bud development

GO:0001707

mesoderm formation

GO:0001823

mesonephros development

GO:0001837

epithelial to mesenchymal transition

GO:0005125

cytokine activity

GO:0005515

protein binding

GO:0005576

extracellular region

GO:0005615

extracellular space

GO:0007411

axon guidance

GO:0008083

growth factor activity

GO:0008201

heparin binding

GO:0009880

embryonic pattern specification

GO:0009887

organ morphogenesis

GO:0010664

negative regulation of striated muscle cell apoptosis

GO:0010862

positive regulation of pathway-restricted SMAD protein phosphorylation

GO:0010942

positive regulation of cell death

GO:0030326

embryonic limb morphogenesis

GO:0030501

positive regulation of bone mineralization

GO:0030509

BMP signaling pathway

GO:0030855

epithelial cell differentiation

GO:0031012

extracellular matrix

GO:0031988

membrane-bounded vesicle

GO:0032088

negative regulation of NF-kappaB transcription factor activity

GO:0032355

response to estradiol stimulus

GO:0033280

response to vitamin D

GO:0034504

protein localization to nucleus

GO:0040007

growth

GO:0042326

negative regulation of phosphorylation

GO:0042347

negative regulation of NF-kappaB import into nucleus

GO:0042475

odontogenesis of dentine-containing tooth

GO:0043065

positive regulation of apoptosis

GO:0043401

steroid hormone mediated signaling pathway

GO:0043407

negative regulation of MAP kinase activity

GO:0043434

response to peptide hormone stimulus

GO:0045665

negative regulation of neuron differentiation

GO:0045666

positive regulation of neuron differentiation

GO:0045669

positive regulation of osteoblast differentiation

GO:0045746

negative regulation of Notch signaling pathway

GO:0045786

negative regulation of cell cycle

GO:0045839

negative regulation of mitosis

GO:0045892

negative regulation of transcription, DNA-dependent

GO:0045893

positive regulation of transcription, DNA-dependent

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

GO:0048468

cell development

GO:0048596

embryonic camera-type eye morphogenesis

GO:0048646

anatomical structure formation involved in morphogenesis

GO:0048754

branching morphogenesis of a tube

GO:0048762

mesenchymal cell differentiation

GO:0048812

neuron projection morphogenesis

GO:0050768

negative regulation of neurogenesis

GO:0051216

cartilage development

GO:0060272

embryonic skeletal joint morphogenesis

GO:0060389

pathway-restricted SMAD protein phosphorylation

GO:0060395

SMAD protein signal transduction

GO:0060445

branching involved in salivary gland morphogenesis

GO:0060485

mesenchyme development

GO:0060548

negative regulation of cell death

GO:0060686

negative regulation of prostatic bud formation

GO:0060687

regulation of branching involved in prostate gland morphogenesis

GO:0071456

cellular response to hypoxia

GO:0072040

negative regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis

GO:0072125

negative regulation of glomerular mesangial cell proliferation

GO:0072133

metanephric mesenchyme morphogenesis

GO:0072134

nephrogenic mesenchyme morphogenesis

GO:0072136

metanephric mesenchymal cell proliferation involved in metanephros development

GO:2000121

regulation of removal of superoxide radicals