Gene basic information
| LiverAtlas Gene ID |
HuLG000458 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
BMPR1A |
|
Synonyms |
10q23del|ACVRLK3|ALK3|CD292|SKR5 |
|
Gene name |
bone morphogenetic protein receptor, type IA |
|
Gene Type |
protein-coding |
|
Chromosome |
10 |
|
Genomics Location |
10q22.3 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:1076
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000166 |
nucleotide binding |
|
GO:0001701 |
in utero embryonic development |
|
GO:0001707 |
mesoderm formation |
|
GO:0001756 |
somitogenesis |
|
GO:0001880 |
Mullerian duct regression |
|
GO:0002053 |
positive regulation of mesenchymal cell proliferation |
|
GO:0003272 |
endocardial cushion formation |
|
GO:0004674 |
protein serine/threonine kinase activity |
|
GO:0004872 |
receptor activity |
|
GO:0005024 |
transforming growth factor beta receptor activity |
|
GO:0005515 |
protein binding |
|
GO:0005524 |
ATP binding |
|
GO:0005886 |
plasma membrane |
|
GO:0005901 |
caveola |
|
GO:0006468 |
protein phosphorylation |
|
GO:0006955 |
immune response |
|
GO:0007179 |
transforming growth factor beta receptor signaling pathway |
|
GO:0007398 |
ectoderm development |
|
GO:0007399 |
nervous system development |
|
GO:0009950 |
dorsal/ventral axis specification |
|
GO:0010862 |
positive regulation of pathway-restricted SMAD protein phosphorylation |
|
GO:0016021 |
integral to membrane |
|
GO:0019827 |
stem cell maintenance |
|
GO:0021983 |
pituitary gland development |
|
GO:0021998 |
neural plate mediolateral regionalization |
|
GO:0030154 |
cell differentiation |
|
GO:0030324 |
lung development |
|
GO:0030501 |
positive regulation of bone mineralization |
|
GO:0030509 |
BMP signaling pathway |
|
GO:0035137 |
hindlimb morphogenesis |
|
GO:0042475 |
odontogenesis of dentine-containing tooth |
|
GO:0042733 |
embryonic digit morphogenesis |
|
GO:0042803 |
protein homodimerization activity |
|
GO:0045669 |
positive regulation of osteoblast differentiation |
|
GO:0046332 |
SMAD binding |
|
GO:0046872 |
metal ion binding |
|
GO:0048339 |
paraxial mesoderm development |
|
GO:0048352 |
paraxial mesoderm structural organization |
|
GO:0048368 |
lateral mesoderm development |
|
GO:0048378 |
regulation of lateral mesodermal cell fate specification |
|
GO:0048382 |
mesendoderm development |
|
GO:0048568 |
embryonic organ development |
|
GO:0048589 |
developmental growth |
|
GO:0050679 |
positive regulation of epithelial cell proliferation |
|
GO:0050768 |
negative regulation of neurogenesis |
|
GO:0051216 |
cartilage development |
|
GO:0060021 |
palate development |
|
GO:0060391 |
positive regulation of SMAD protein import into nucleus |
|
GO:0060896 |
neural plate pattern specification |
|
GO:0060914 |
heart formation |
