Gene basic information
| LiverAtlas Gene ID |
HuLG000474 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
BRAF |
|
Synonyms |
BNRAF1|BRAF1|FLJ95109|MGC126806|MGC138284|NS7|RAFB1 |
|
Gene name |
v-raf murine sarcoma viral oncogene homolog B1 |
|
Gene Type |
protein-coding |
|
Chromosome |
7 |
|
Genomics Location |
7q34 |
|
Known cancer genes |
Yes |
|
Protein products |
Serine/threonine-protein kinase B-raf |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:1097
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000166 |
nucleotide binding |
|
GO:0000186 |
activation of MAPKK activity |
|
GO:0004672 |
protein kinase activity |
|
GO:0004674 |
protein serine/threonine kinase activity |
|
GO:0004709 |
MAP kinase kinase kinase activity |
|
GO:0005057 |
receptor signaling protein activity |
|
GO:0005515 |
protein binding |
|
GO:0005524 |
ATP binding |
|
GO:0005625 |
soluble fraction |
|
GO:0005634 |
nucleus |
|
GO:0005737 |
cytoplasm |
|
GO:0005829 |
cytosol |
|
GO:0005886 |
plasma membrane |
|
GO:0006468 |
protein phosphorylation |
|
GO:0006916 |
anti-apoptosis |
|
GO:0007264 |
small GTPase mediated signal transduction |
|
GO:0007268 |
synaptic transmission |
|
GO:0009887 |
organ morphogenesis |
|
GO:0019717 |
synaptosome |
|
GO:0031434 |
mitogen-activated protein kinase kinase binding |
|
GO:0033138 |
positive regulation of peptidyl-serine phosphorylation |
|
GO:0043066 |
negative regulation of apoptosis |
|
GO:0043434 |
response to peptide hormone stimulus |
|
GO:0043524 |
negative regulation of neuron apoptosis |
|
GO:0046872 |
metal ion binding |
|
GO:0046982 |
protein heterodimerization activity |
|
GO:0048011 |
nerve growth factor receptor signaling pathway |
|
GO:0051291 |
protein heterooligomerization |
|
GO:0051591 |
response to cAMP |
|
GO:0070374 |
positive regulation of ERK1 and ERK2 cascade |
