Gene basic information
| LiverAtlas Gene ID |
HuLG000491 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
BUB1 |
|
Synonyms |
BUB1A|BUB1L|hBUB1 |
|
Gene name |
budding uninhibited by benzimidazoles 1 homolog (yeast) |
|
Gene Type |
protein-coding |
|
Chromosome |
2 |
|
Genomics Location |
2q14 |
|
Known cancer genes |
Yes |
|
Protein products |
Mitotic checkpoint serine/threonine-protein kinase BUB1 BUB1 budding uninhibited by benzimidazoles 1 homolog (Yeast) |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:1148
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000087 |
M phase of mitotic cell cycle |
|
GO:0000166 |
nucleotide binding |
|
GO:0000236 |
mitotic prometaphase |
|
GO:0000278 |
mitotic cell cycle |
|
GO:0000776 |
kinetochore |
|
GO:0000777 |
condensed chromosome kinetochore |
|
GO:0000780 |
condensed nuclear chromosome, centromeric region |
|
GO:0004672 |
protein kinase activity |
|
GO:0004674 |
protein serine/threonine kinase activity |
|
GO:0005515 |
protein binding |
|
GO:0005524 |
ATP binding |
|
GO:0005634 |
nucleus |
|
GO:0005694 |
chromosome |
|
GO:0005829 |
cytosol |
|
GO:0006468 |
protein phosphorylation |
|
GO:0006915 |
apoptosis |
|
GO:0007063 |
regulation of sister chromatid cohesion |
|
GO:0007093 |
mitotic cell cycle checkpoint |
|
GO:0007094 |
mitotic cell cycle spindle assembly checkpoint |
|
GO:0009790 |
embryo development |
|
GO:0044419 |
interspecies interaction between organisms |
|
GO:0051301 |
cell division |
|
GO:0051983 |
regulation of chromosome segregation |
|
GO:0071173 |
spindle assembly checkpoint |
