Gene basic information
| LiverAtlas Gene ID |
HuLG000492 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
BUB1B |
|
Synonyms |
BUB1beta|BUBR1|Bub1A|MAD3L|SSK1|hBUBR1 |
|
Gene name |
budding uninhibited by benzimidazoles 1 homolog beta (yeast) |
|
Gene Type |
protein-coding |
|
Chromosome |
15 |
|
Genomics Location |
15q15 |
|
Known cancer genes |
Yes |
|
Protein products |
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:1149
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000075 |
cell cycle checkpoint |
|
GO:0000087 |
M phase of mitotic cell cycle |
|
GO:0000166 |
nucleotide binding |
|
GO:0000236 |
mitotic prometaphase |
|
GO:0000278 |
mitotic cell cycle |
|
GO:0000776 |
kinetochore |
|
GO:0000777 |
condensed chromosome kinetochore |
|
GO:0000940 |
condensed chromosome outer kinetochore |
|
GO:0004672 |
protein kinase activity |
|
GO:0004674 |
protein serine/threonine kinase activity |
|
GO:0005515 |
protein binding |
|
GO:0005524 |
ATP binding |
|
GO:0005634 |
nucleus |
|
GO:0005680 |
anaphase-promoting complex |
|
GO:0005694 |
chromosome |
|
GO:0005737 |
cytoplasm |
|
GO:0005815 |
microtubule organizing center |
|
GO:0005829 |
cytosol |
|
GO:0005856 |
cytoskeleton |
|
GO:0006468 |
protein phosphorylation |
|
GO:0006915 |
apoptosis |
|
GO:0007049 |
cell cycle |
|
GO:0007051 |
spindle organization |
|
GO:0007067 |
mitosis |
|
GO:0007091 |
mitotic metaphase/anaphase transition |
|
GO:0007093 |
mitotic cell cycle checkpoint |
|
GO:0007094 |
mitotic cell cycle spindle assembly checkpoint |
|
GO:0008283 |
cell proliferation |
|
GO:0031145 |
anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process |
|
GO:0034501 |
protein localization to kinetochore |
|
GO:0048015 |
phosphatidylinositol-mediated signaling |
|
GO:0048471 |
perinuclear region of cytoplasm |
|
GO:0051233 |
spindle midzone |
|
GO:0051301 |
cell division |
|
GO:0051436 |
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle |
|
GO:0051439 |
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle |
