Gene basic information
| LiverAtlas Gene ID |
HuLG000510 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
C5 |
|
Synonyms |
CPAMD4|FLJ17816|FLJ17822|MGC142298 |
|
Gene name |
complement component 5 |
|
Gene Type |
protein-coding |
|
Chromosome |
9 |
|
Genomics Location |
9q33-q34 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
Liver fibrosis and liver cirrhosis Liver fibrosis and liver cirrhosis caused by hepatitis C infection |
|
Database cross reference |
HGNC:1331
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000187 |
activation of MAPK activity |
|
GO:0001701 |
in utero embryonic development |
|
GO:0004866 |
endopeptidase inhibitor activity |
|
GO:0005102 |
receptor binding |
|
GO:0005576 |
extracellular region |
|
GO:0005579 |
membrane attack complex |
|
GO:0005615 |
extracellular space |
|
GO:0006935 |
chemotaxis |
|
GO:0006950 |
response to stress |
|
GO:0006954 |
inflammatory response |
|
GO:0006956 |
complement activation |
|
GO:0006957 |
complement activation, alternative pathway |
|
GO:0006958 |
complement activation, classical pathway |
|
GO:0007166 |
cell surface receptor linked signaling pathway |
|
GO:0007186 |
G-protein coupled receptor protein signaling pathway |
|
GO:0008009 |
chemokine activity |
|
GO:0010575 |
positive regulation vascular endothelial growth factor production |
|
GO:0010760 |
negative regulation of macrophage chemotaxis |
|
GO:0019835 |
cytolysis |
|
GO:0045087 |
innate immune response |
|
GO:0045766 |
positive regulation of angiogenesis |
|
GO:0090197 |
positive regulation of chemokine secretion |
