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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000514

Entrez Gene ID

731

Official Gene Symbol

C8A

Gene name

complement component 8, alpha polypeptide

Gene Type

protein-coding

Chromosome

1

Genomics Location

1p32

Known cancer genes

Yes

Protein products

Complement component C8 alpha chain

C8A protein

Related liver disease name

Hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Hepatocellular carcinoma

Database cross reference

HGNC:1352
MIM:120950
Ensembl:ENSG00000157131
HPRD:00409
RefSeq Genomic nucleotide accession:AC_000044
RefSeq Genomic nucleotide gi:89161184

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0005576

extracellular region

GO:0005579

membrane attack complex

GO:0005615

extracellular space

GO:0005886

plasma membrane

GO:0006955

immune response

GO:0006956

complement activation

GO:0006957

complement activation, alternative pathway

GO:0006958

complement activation, classical pathway

GO:0016020

membrane

GO:0016021

integral to membrane

GO:0019835

cytolysis

GO:0045087

innate immune response