HuLG000534

Entrez Gene ID

760

Official Gene Symbol

CA2

Synonyms

CANII|CAII|Car2

Gene name

carbonic anhydrase II

Gene Type

protein-coding

Chromosome

8

Genomics Location

8q22

Known cancer genes

Yes

Protein products

Carbonic anhydrase 2

Related liver disease name

Liver fibrosis and liver cirrhosis

Autoimmune hepatitis

Hepatocellular carcinoma

Primary biliary cirrhosis

Database cross reference

HGNC:1373
MIM:611492
Ensembl:ENSG00000104267
HPRD:02023
RefSeq Genomic nucleotide accession:AC_000051
RefSeq Genomic nucleotide gi:89161214

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

GO annotation

GO:0001822

kidney development

GO:0002009

morphogenesis of an epithelium

GO:0004089

carbonate dehydratase activity

GO:0005615

extracellular space

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0005902

microvillus

GO:0006730

one-carbon metabolic process

GO:0006950

response to stress

GO:0008270

zinc ion binding

GO:0009268

response to pH

GO:0010033

response to organic substance

GO:0010043

response to zinc ion

GO:0015670

carbon dioxide transport

GO:0016323

basolateral plasma membrane

GO:0016829

lyase activity

GO:0030424

axon

GO:0032849

positive regulation of cellular pH reduction

GO:0042475

odontogenesis of dentine-containing tooth

GO:0043627

response to estrogen stimulus

GO:0045177

apical part of cell

GO:0045672

positive regulation of osteoclast differentiation

GO:0045780

positive regulation of bone resorption

GO:0046872

metal ion binding

GO:0046903

secretion