Gene basic information
| LiverAtlas Gene ID |
HuLG000551 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
DDR1 |
|
Synonyms |
CAK|CD167|DDR|EDDR1|HGK2|MCK10|NEP|NTRK4|PTK3|PTK3A|RTK6|TRKE |
|
Gene name |
discoidin domain receptor tyrosine kinase 1 |
|
Gene Type |
protein-coding |
|
Chromosome |
6 |
|
Genomics Location |
6p21.3 |
|
Known cancer genes |
Yes |
|
Protein products |
cDNA FLJ56035, highly similar to Epithelial discoidin domain-containing receptor 1 (EC 2.7.10.1) Epithelial discoidin domain-containing receptor 1 |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:2730
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000166 |
nucleotide binding |
|
GO:0001558 |
regulation of cell growth |
|
GO:0001952 |
regulation of cell-matrix adhesion |
|
GO:0004714 |
transmembrane receptor protein tyrosine kinase activity |
|
GO:0004872 |
receptor activity |
|
GO:0005515 |
protein binding |
|
GO:0005524 |
ATP binding |
|
GO:0005576 |
extracellular region |
|
GO:0005886 |
plasma membrane |
|
GO:0005887 |
integral to plasma membrane |
|
GO:0007155 |
cell adhesion |
|
GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway |
|
GO:0007566 |
embryo implantation |
|
GO:0008285 |
negative regulation of cell proliferation |
|
GO:0016323 |
basolateral plasma membrane |
|
GO:0018108 |
peptidyl-tyrosine phosphorylation |
|
GO:0031100 |
organ regeneration |
|
GO:0043583 |
ear development |
|
GO:0043588 |
skin development |
|
GO:0051789 |
response to protein stimulus |
|
GO:0060444 |
branching involved in mammary gland duct morphogenesis |
|
GO:0060749 |
mammary gland alveolus development |
