Gene basic information
LiverAtlas Gene ID |
HuLG000571 |
Entrez Gene ID |
|
Official Gene Symbol |
CALR |
Synonyms |
CRT|FLJ26680|RO|SSA|cC1qR |
Gene name |
calreticulin |
Gene Type |
protein-coding |
Chromosome |
19 |
Genomics Location |
19p13.3-p13.2 |
Known cancer genes |
Yes |
Protein products |
|
Related liver disease name |
|
Database cross reference |
HGNC:1455
|
Liver relevance
HCC significant genes |
Yes/No |
Yes |
Evidence |
EHCO |
|
Quality score |
|
Ontology annotation
GO ID |
GO annotation |
GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
GO:0001669 |
acrosomal vesicle |
GO:0001849 |
complement component C1q binding |
GO:0002502 |
peptide antigen assembly with MHC class I protein complex |
GO:0003677 |
DNA binding |
GO:0003729 |
mRNA binding |
GO:0005178 |
integrin binding |
GO:0005506 |
iron ion binding |
GO:0005509 |
calcium ion binding |
GO:0005515 |
protein binding |
GO:0005529 |
sugar binding |
GO:0005576 |
extracellular region |
GO:0005578 |
proteinaceous extracellular matrix |
GO:0005615 |
extracellular space |
GO:0005622 |
intracellular |
GO:0005625 |
soluble fraction |
GO:0005634 |
nucleus |
GO:0005737 |
cytoplasm |
GO:0005783 |
endoplasmic reticulum |
GO:0005788 |
endoplasmic reticulum lumen |
GO:0005792 |
microsome |
GO:0005794 |
Golgi apparatus |
GO:0005829 |
cytosol |
GO:0005844 |
polysome |
GO:0006355 |
regulation of transcription, DNA-dependent |
GO:0006457 |
protein folding |
GO:0006611 |
protein export from nucleus |
GO:0006874 |
cellular calcium ion homeostasis |
GO:0007050 |
cell cycle arrest |
GO:0007283 |
spermatogenesis |
GO:0008270 |
zinc ion binding |
GO:0008284 |
positive regulation of cell proliferation |
GO:0009897 |
external side of plasma membrane |
GO:0009986 |
cell surface |
GO:0016529 |
sarcoplasmic reticulum |
GO:0017148 |
negative regulation of translation |
GO:0018279 |
protein N-linked glycosylation via asparagine |
GO:0022417 |
protein maturation by protein folding |
GO:0030246 |
carbohydrate binding |
GO:0030866 |
cortical actin cytoskeleton organization |
GO:0031625 |
ubiquitin protein ligase binding |
GO:0032355 |
response to estradiol stimulus |
GO:0033144 |
negative regulation of steroid hormone receptor signaling pathway |
GO:0033574 |
response to testosterone stimulus |
GO:0040020 |
regulation of meiosis |
GO:0042277 |
peptide binding |
GO:0042493 |
response to drug |
GO:0042562 |
hormone binding |
GO:0042824 |
MHC class I peptide loading complex |
GO:0042921 |
glucocorticoid receptor signaling pathway |
GO:0042981 |
regulation of apoptosis |
GO:0043687 |
post-translational protein modification |
GO:0044183 |
protein binding involved in protein folding |
GO:0044267 |
cellular protein metabolic process |
GO:0045665 |
negative regulation of neuron differentiation |
GO:0045740 |
positive regulation of DNA replication |
GO:0045787 |
positive regulation of cell cycle |
GO:0048387 |
negative regulation of retinoic acid receptor signaling pathway |
GO:0048471 |
perinuclear region of cytoplasm |
GO:0050681 |
androgen receptor binding |
GO:0050766 |
positive regulation of phagocytosis |
GO:0050821 |
protein stabilization |
GO:0051082 |
unfolded protein binding |
GO:0051087 |
chaperone binding |
GO:0051208 |
sequestering of calcium ion |
GO:0055007 |
cardiac muscle cell differentiation |
GO:0071285 |
cellular response to lithium ion |
GO:0071310 |
cellular response to organic substance |
GO:0090398 |
cellular senescence |