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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000582

Entrez Gene ID

823

Official Gene Symbol

CAPN1

Synonyms

CANP|CANP1|CANPL1|muCANP|muCL

Gene name

calpain 1, (mu/I) large subunit

Gene Type

protein-coding

Chromosome

11

Genomics Location

11q13

Known cancer genes

Yes

Protein products

Uncharacterized protein

cDNA, FLJ96627, highly similar to Homo sapiens calpain 1, (mu/I) large subunit (CAPN1), mRNA

cDNA FLJ53224, highly similar to Calpain-1 catalytic subunit (EC 3.4.22.52)

Calpain-1 catalytic subunit

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:1476
MIM:114220
Ensembl:ENSG00000014216
HPRD:00253
RefSeq Genomic nucleotide accession:AC_000054
RefSeq Genomic nucleotide gi:89161188

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0004198

calcium-dependent cysteine-type endopeptidase activity

GO:0005509

calcium ion binding

GO:0005515

protein binding

GO:0005622

intracellular

GO:0005737

cytoplasm

GO:0005886

plasma membrane

GO:0006508

proteolysis

GO:0008233

peptidase activity

GO:0008284

positive regulation of cell proliferation