Gene basic information
| LiverAtlas Gene ID |
HuLG000593 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
CASP1 |
|
Synonyms |
ICE|IL1BC|P45 |
|
Gene name |
caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) |
|
Gene Type |
protein-coding |
|
Chromosome |
11 |
|
Genomics Location |
11q23 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:1499
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
OncoDB |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0004197 |
cysteine-type endopeptidase activity |
|
GO:0005515 |
protein binding |
|
GO:0005622 |
intracellular |
|
GO:0005737 |
cytoplasm |
|
GO:0005829 |
cytosol |
|
GO:0006508 |
proteolysis |
|
GO:0006915 |
apoptosis |
|
GO:0006919 |
activation of caspase activity |
|
GO:0007165 |
signal transduction |
|
GO:0008233 |
peptidase activity |
|
GO:0008656 |
caspase activator activity |
|
GO:0042981 |
regulation of apoptosis |
|
GO:0043123 |
positive regulation of I-kappaB kinase/NF-kappaB cascade |
|
GO:0071260 |
cellular response to mechanical stimulus |
|
GO:0071310 |
cellular response to organic substance |
