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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000596

Entrez Gene ID

837

Official Gene Symbol

CASP4

Synonyms

ICE(rel)II|ICERELNII|ICHN2|Mih1/TX|TX

Gene name

caspase 4, apoptosis-related cysteine peptidase

Gene Type

protein-coding

Chromosome

11

Genomics Location

11q22.2-q22.3

Known cancer genes

Yes

Protein products

Caspase 4, apoptosis-related cysteine peptidase

Caspase 4, apoptosis-related cysteine peptidase, isoform CRA c

Caspase-4

Related liver disease name

Hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Hepatocellular carcinoma

Database cross reference

HGNC:1505
MIM:602664
Ensembl:ENSG00000196954
HPRD:04047
RefSeq Genomic nucleotide accession:AC_000054
RefSeq Genomic nucleotide gi:89161188

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0004197

cysteine-type endopeptidase activity

GO:0005515

protein binding

GO:0005622

intracellular

GO:0006508

proteolysis

GO:0006915

apoptosis

GO:0006917

induction of apoptosis

GO:0008233

peptidase activity

GO:0042981

regulation of apoptosis