Gene basic information
| LiverAtlas Gene ID |
HuLG000602 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
CASP10 |
|
Synonyms |
ALPS2|FLICE2|MCH4 |
|
Gene name |
caspase 10, apoptosis-related cysteine peptidase |
|
Gene Type |
protein-coding |
|
Chromosome |
2 |
|
Genomics Location |
2q33-q34 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:1500
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0004197 |
cysteine-type endopeptidase activity |
|
GO:0005515 |
protein binding |
|
GO:0005829 |
cytosol |
|
GO:0005886 |
plasma membrane |
|
GO:0006508 |
proteolysis |
|
GO:0006915 |
apoptosis |
|
GO:0006917 |
induction of apoptosis |
|
GO:0008233 |
peptidase activity |
|
GO:0008624 |
induction of apoptosis by extracellular signals |
|
GO:0042802 |
identical protein binding |
|
GO:0042981 |
regulation of apoptosis |
|
GO:0043123 |
positive regulation of I-kappaB kinase/NF-kappaB cascade |
