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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG000606

Entrez Gene ID

847

Official Gene Symbol

CAT

Synonyms

MGC138422|MGC138424

Gene name

catalase

Gene Type

protein-coding

Chromosome

11

Genomics Location

11p13

Known cancer genes

Yes

Protein products

Catalase

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Hepatitis A

Hepatitis B

Chronic hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Alcoholic liver cirrhosis

Hepatocellular carcinoma

Database cross reference

HGNC:1516
MIM:115500
Ensembl:ENSG00000121691
HPRD:00282
RefSeq Genomic nucleotide accession:AC_000054
RefSeq Genomic nucleotide gi:89161188

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000302

response to reactive oxygen species

GO:0004096

catalase activity

GO:0005515

protein binding

GO:0005758

mitochondrial intermembrane space

GO:0005764

lysosome

GO:0005777

peroxisome

GO:0005778

peroxisomal membrane

GO:0005782

peroxisomal matrix

GO:0005783

endoplasmic reticulum

GO:0005794

Golgi apparatus

GO:0005829

cytosol

GO:0005886

plasma membrane

GO:0006144

purine base metabolic process

GO:0006195

purine nucleotide catabolic process

GO:0009650

UV protection

GO:0016684

oxidoreductase activity, acting on peroxide as acceptor

GO:0020037

heme binding

GO:0042744

hydrogen peroxide catabolic process

GO:0042803

protein homodimerization activity

GO:0043066

negative regulation of apoptosis

GO:0046872

metal ion binding

GO:0050661

NADP binding

GO:0051262

protein tetramerization

GO:0051781

positive regulation of cell division

GO:0055086

nucleobase, nucleoside and nucleotide metabolic process